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US6362375B1
Process for the preparation of aryl ketones generating reduced amounts of toxic byproducts
Publication/Patent Number: US6362375B1 Publication Date: 2002-03-26 Application Number: 09/454,083 Filing Date: 1999-12-03 Inventor: Walker, Martin   Assignee: College of the Holy Cross   IPC: C07C4546 Abstract: An efficient, cost-effective method useful for the production of aryl ketones that minimizes the generation of toxic byproducts is disclosed. The method utilizes a metal triflate salt to catalyze the reaction between the carboxylic acid substrate and the aromatic substrate. The water generated by the reaction is collected and removed during the process.