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No. Publication Number Title Publication/Patent Number Publication/Patent Number Publication Date Publication Date
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1
EP3865150A1
COMBINATION THERAPY WITH DENGUE VIRUS AND DENDRITIC CELLS
Publication/Patent Number: EP3865150A1 Publication Date: 2021-08-18 Application Number: 21154546.2 Filing Date: 2016-09-23 Inventor: Lyday, Bruce W   Chen, Tony   Assignee: Primevax Immuno-Oncology, Inc.   IPC: A61K39/00 Abstract: Described herein are compositions and methods for treating a disease, particularly a cancer, with primed dendritic cells recognizing a tumor antigen. The methods may comprise storing, shipping and/or culturing dendritic cells, where the dendritic cells are stored on a hard surface. Lysis protocols are described where the lysis does not result in complete lysis of cells in order to provide cell surface molecules maintained in a cell surface-embedded state. Non-lethal Dengue virus strains are also provided for therapeutic purposes.
2
US2021038766A1
METHOD OF MAKING, MANUFACTURING OR PRODUCING ORTHOPEDIC SOFT TISSUE
Publication/Patent Number: US2021038766A1 Publication Date: 2021-02-11 Application Number: 16/757,191 Filing Date: 2018-10-19 Inventor: Chen, Tony   Maher, Suzanne A.   Warren, Russell   Assignee: NEW YORK SOCIETY FOR THE RUPTURED AND CRIPPLED MAINTAINING THE HOSPITAL FOR SPECIAL SURGERY   IPC: A61L27/36 Abstract: An improved method of making, manufacturing and/or producing engineered orthopedic soft tissue including cartilage, meniscus, annulus fibrosus, and tendon/ligaments which results in engineered soft tissue in which the fibers are aligned the same or nearly the same as naturally occurring tissue. The present invention also includes molds and other apparatus for carrying out the methods of the invention and kits.
3
US11040124B2
Method of and a mold for the manufacture, making and/or production of a multi-component implant, device, construct or material
Publication/Patent Number: US11040124B2 Publication Date: 2021-06-22 Application Number: 16/498,211 Filing Date: 2018-05-01 Inventor: Maher, Suzanne A.   Chen, Tony   Warren, Russell   Assignee: NEW YORK SOCIETY FOR THE RUPTURED AND CRIPPLED MAINTAINING THE HOSPITAL FOR SPECIAL SURGERY   IPC: B29C45/03 Abstract: An improved new method of making a multi-component implant comprising a solid hydrogel, a porous hydrogel, and a porous rigid base suitable for implantation into a mammal, to treat, repair or replace defects and/or injury biological tissue as well as the implant made from the improved method. The invention also includes an improved method for making devices, constructs, and materials comprising a hydrogel and a porous rigid material. The invention also includes a mold and kits for performing the methods.
4
EP3824621A1
SYSTEMS AND METHODS FOR MULTI-MODAL SENSING OF DEPTH IN VISION SYSTEMS FOR AUTOMATED SURGICAL ROBOTS
Publication/Patent Number: EP3824621A1 Publication Date: 2021-05-26 Application Number: 19838270.7 Filing Date: 2019-07-19 Inventor: Calef, Thomas J.   Chen, Tina P.   Demaio, Emanuel   Chen, Tony   Buharin, Vasiliy Evgenyevich   Ruehlman, Michael G.   Assignee: Activ Surgical, Inc.   IPC: H04N13/271
5
US2021236226A1
SYSTEMS AND METHODS FOR MULTI-MODAL SENSING OF DEPTH IN VISION SYSTEMS FOR AUTOMATED SURGICAL ROBOTS
Publication/Patent Number: US2021236226A1 Publication Date: 2021-08-05 Application Number: 17/150,701 Filing Date: 2021-01-15 Inventor: Calef, Thomas J.   Chen, Tina P.   Demaio, Emanuel   Chen, Tony   Buharin, Vasiliy Evgenyevich   Ruehlman, Michael G.   Assignee: Activ Surgical, Inc.   IPC: A61B90/00 Abstract: Systems and methods for multi-modal sensing of three-dimensional position information of the surface of an object are disclosed. In particular, multiple visualization modalities are each used to collect distinctive positional information of a surface of an object. Each of the computed positional information is combined using weighting factors to compute a final, weighted three-dimensional position. In various embodiments, a first depth may be recorded using fiducial markers, a second depth may be recorded using a structured light pattern, and a third depth may be recorded using a light-field camera. Weighting factors may be applied to each of the recorded depths and a final, weighted depth may be computed.
6
US2021085853A1
SYSTEMS AND METHODS FOR AUTOMATED ASSESSMENT AND MONITORING OF BODILY FLUIDS
Publication/Patent Number: US2021085853A1 Publication Date: 2021-03-25 Application Number: 16/976,397 Filing Date: 2019-03-01 Inventor: Chen, Tony   Sun, Jialu   Sweet, Robert Marten   Gore, John Lawrence   Liu, Jonathan Teng-chieh   Posner, Jonathan Dov   Randad, Akshay Purushottamji   Branch, Allegra Joyce   Kampianakis, Eleftherios   Covelli, Velez Claudia Jimena   Assignee: University of Washington   IPC: A61M3/02 Abstract: Systems and methods for automated assessment and monitoring of bodily fluids are disclosed. In one embodiment, a system for provisioning a treatment composition to a bladder of a patient includes: an irrigation bag that carries the treatment composition; a catheter configured for connecting the irrigation bag to the bladder; a flow regulator configured for controlling a flow of the treatment composition from the irrigation bag to the bladder; and a drainage bag in fluid communication with the bladder through a drainage tubing of the catheter. The drainage tubing is configured for draining urine from the bladder. The system also includes: a first sensor for detecting a first amount of the treatment composition in the irrigation bag; a second sensor for detecting a second amount of urine in the drainage bag; a third sensor for detecting a concentration of particles in the urine carried by the drainage bag; and a controller.
7
US2021019679A1
LOCATION AND MARKING SYSTEM AND SERVER
Publication/Patent Number: US2021019679A1 Publication Date: 2021-01-21 Application Number: 16/932,044 Filing Date: 2020-07-17 Inventor: Warner, Shelbey   Wolf, Bob   Glenn, William   Hansen, Michael   Sharif, Morgan   Klemm, Jason   Scofield, Zac   Dotson, Eddie   Huston, Travis   Walker, Steven   Glass, Michael   Buckles, Patrick   Chen, Tony   Jasti, Siva   Assignee: PACIFIC GAS AND ELECTRIC COMPANY   IPC: G06Q10/06 Abstract: A novel location and marking system is configured to provide a seamless in-the-field access to resource and asset information databases with automated functionality that effectively and more efficiently manages, controls, and distributes data according to some embodiments. In some embodiments, such systems can enable utilities to manage assets in real-time, provide map asset status, and provide automatic ticket routing, dispatching and management. For example, in some embodiments, the system is configured to generate maps with identifiers or components of an active division including tickets of one or more assets of an active division. These assets include sites of residential and business gas, electrical, and/or water and sewer conduits and metering systems, as well as related underground infrastructure that can be susceptible to earthquakes, ground disturbances, and other emergency situations according to some embodiments.
8
US2021034027A1
ELECTRIC POWER GRID INSPECTION AND MANAGEMENT SYSTEM
Publication/Patent Number: US2021034027A1 Publication Date: 2021-02-04 Application Number: 16/942,060 Filing Date: 2020-07-29 Inventor: Datta, Kunal   Chen, Tony   Kwan, Marcella   Buckles, Patrick   Locatelli, Michael James   Alapat, Teresa   Joseph, Maria   Glass, Michael S.   Mello, Jonathan   Faizan, Khushar   Li, Xiwang   Assignee: PACIFIC GAS AND ELECTRIC COMPANY   IPC: G05B19/048 Abstract: In some embodiments, the system is directed to an autonomous inspection system for electrical grid components. In some embodiments, the system collects electrical grid component data using an autonomous drone and then transmits the inspection data to one or more computers. In some embodiments, the system includes artificial intelligence that analysis the data and identifies electrical grid components defects and provides a model highlighting the defects to a user. In some embodiments, the system enables a user to train the artificial intelligence by providing feedback for models where defects or components are not properly identified.
9
AU2018285525A1
Compositions and methods for cancer therapy with dengue virus and dendritic cells
Publication/Patent Number: AU2018285525A1 Publication Date: 2020-01-30 Application Number: 2018285525 Filing Date: 2018-06-14 Inventor: Chen, Tony   Lyday, Bruce W.   Assignee: PrimeVax Immuno-Oncology Inc.   IPC: A61P35/00
10
EP3638303A1
COMPOSITIONS AND METHODS FOR CANCER THERAPY WITH DENGUE VIRUS AND DENDRITIC CELLS
Publication/Patent Number: EP3638303A1 Publication Date: 2020-04-22 Application Number: 18817312.4 Filing Date: 2018-06-14 Inventor: Lyday, Bruce W.   Chen, Tony   Assignee: Primevax Immuno-Oncology, Inc.   IPC: A61K39/12
11
US2020360497A1
COMPOSITIONS AND METHODS FOR PRODUCING DENDRITIC CELLS
Publication/Patent Number: US2020360497A1 Publication Date: 2020-11-19 Application Number: 16/942,058 Filing Date: 2020-07-29 Inventor: Lyday, Bruce W.   Chen, Tony   Assignee: PrimeVax Immuno-Oncology, Inc.   IPC: A61K39/00 Abstract: Described herein are compositions and methods for treating a disease, particularly a cancer, with primed dendritic cells recognizing a tumor antigen. The methods may comprise storing, shipping and/or culturing dendritic cells, where the dendritic cells are stored on a hard surface. Lysis protocols are described where the lysis does not result in complete lysis of cells in order to provide cell surface molecules maintained in a cell surface-embedded state. Non-lethal Dengue virus strains are also provided for therapeutic purposes.
12
US2020121745A1
COMPOSITIONS AND METHODS FOR CANCER THERAPY WITH DENGUE VIRUS AND DENDRITIC CELLS
Publication/Patent Number: US2020121745A1 Publication Date: 2020-04-23 Application Number: 16/714,370 Filing Date: 2019-12-13 Inventor: Lyday, Bruce W.   Chen, Tony   Assignee: PrimeVax Immuno-Oncology, Inc.   IPC: A61K35/76 Abstract: Described herein are compositions and methods for treating a disease, particularly a melanoma, with a Dengue Virus and, optionally, primed dendritic cells recognizing a tumor antigen. Lysis protocols are described where the lysis does not result in complete or less than complete lysis of cells in order to provide cell surface molecules maintained in a cell surface-embedded state. Non-lethal Dengue virus strains are also provided for therapeutic purposes.
13
US10765727B2
Compositions and methods for producing dendritic cells
Publication/Patent Number: US10765727B2 Publication Date: 2020-09-08 Application Number: 15/275,073 Filing Date: 2016-09-23 Inventor: Lyday, Bruce W.   Chen, Tony   Assignee: Primevax Immuno-Oncology, Inc.   IPC: A61K39/00 Abstract: Described herein are compositions and methods for treating a disease, particularly a cancer, with primed dendritic cells recognizing a tumor antigen. The methods may comprise storing, shipping and/or culturing dendritic cells, where the dendritic cells are stored on a hard surface. Lysis protocols are described where the lysis does not result in complete lysis of cells in order to provide cell surface molecules maintained in a cell surface-embedded state. Non-lethal Dengue virus strains are also provided for therapeutic purposes.
14
EP3618773A1
A METHOD OF AND A MOLD FOR THE MANUFACTURE, MAKING AND/OR PRODUCTION OF A MULTI-COMPONENT IMPLANT, DEVICE, CONSTRUCT OR MATERIAL
Publication/Patent Number: EP3618773A1 Publication Date: 2020-03-11 Application Number: 18795213.0 Filing Date: 2018-05-01 Inventor: Maher, Suzanne A.   Chen, Tony   Warren, Russell   Assignee: New York Society for the Ruptured and Crippled Maintaining the Hospital for Special Surgery   IPC: A61F2/30
15
USD873476S1
Bezel for automobile headlamp
Publication/Patent Number: USD873476S1 Publication Date: 2020-01-21 Application Number: 35/505,800 Filing Date: 2018-04-03 Inventor: Rogelio, Flores   Chen, Tony   Arnold, Bradley   Assignee: Hyundai Motor Company   Kia Motors Corporation   IPC:
16
US2020376168A1
A METHOD OF AND A MOLD FOR THE MANUFACTURE, MAKING AND/OR PRODUCTION OF A MULTI-COMPONENT IMPLANT, DEVICE, CONSTRUCT OR MATERIAL
Publication/Patent Number: US2020376168A1 Publication Date: 2020-12-03 Application Number: 16/498,211 Filing Date: 2018-05-01 Inventor: Maher, Suzanne A.   Chen, Tony   Warren, Russell   Assignee: NEW YORK SOCIETY FOR THE RUPTURED AND CRIPPLED MAINTAINING THE HOSPITAL FOR SPECIAL SURGERY   IPC: A61L27/52 Abstract: An improved new method of making a multi-component implant comprising a solid hydrogel, a porous hydrogel, and a porous rigid base suitable for implantation into a mammal, to treat, repair or replace defects and/or injury biological tissue as well as the implant made from the improved method. The invention also includes an improved method for making devices, constructs, and materials comprising a hydrogel and a porous rigid material. The invention also includes a mold and kits for performing the methods.
17
EP3697341A2
METHOD OF MAKING, MANUFACTURING OR PRODUCING ORTHOPEDIC SOFT TISSUE
Publication/Patent Number: EP3697341A2 Publication Date: 2020-08-26 Application Number: 18867715.7 Filing Date: 2018-10-19 Inventor: Chen, Tony   Maher, Suzanne A.   Warren, Russell   Assignee: New York Society for the Ruptured and Crippled Maintaining the Hospital for Special Surgery   IPC: A61F2/08
18
US10583224B2
Multi-component non-biodegradable implant, a method of making and a method of implantation
Publication/Patent Number: US10583224B2 Publication Date: 2020-03-10 Application Number: 15/370,832 Filing Date: 2016-12-06 Inventor: Maher, Suzanne A.   Chen, Tony   Lipman, Joseph D.   Torzilli, Peter   Warren, Russell   Assignee: NEW YORK SOCIETY FOR THE RUPTURED AND CRIPPLED MAINTAINING THE HOSPITAL FOR SPECIAL SURGERY   IPC: A61F2/30 Abstract: An implant comprising at least three components, namely, a solid hydrogel, a porous hydrogel adjacent to or surrounding the solid hydrogel (together considered “the hydrogel”), and a porous rigid base. The solid hydrogel and porous rigid base carry joint load, and the porous hydrogel layer and the porous rigid base allow for cellular migration into and around the implant. The invention is also a novel method of manufacturing the implant, a novel method of implanting the implant, and a method of treating, repairing or replacing biological tissue, more preferably musculoskeletal tissue, with the implant.
19
WO2020018931A1
SYSTEMS AND METHODS FOR MULTI-MODAL SENSING OF DEPTH IN VISION SYSTEMS FOR AUTOMATED SURGICAL ROBOTS
Publication/Patent Number: WO2020018931A1 Publication Date: 2020-01-23 Application Number: 2019042647 Filing Date: 2019-07-19 Inventor: Chen, Tony   Calef, Thomas J.   Chen, Tina P.   Buharin, Vasiliy Evgenyevich   Ruehlman, Michael G.   Demaio, Emanuel   Assignee: ACTIV SURGICAL, INC.   IPC: H04N13/271 Abstract: Systems and methods for multi-modal sensing of three-dimensional position information of the surface of an object are disclosed. In particular, multiple visualization modalities are each used to collect distinctive positional information of a surface of an object. Each of the computed positional information is combined using weighting factors to compute a final, weighted three-dimensional position. In various embodiments, a first depth may be recorded using fiducial markers, a second depth may be recorded using a structured light pattern, and a third depth may be recorded using a light-field camera. Weighting factors may be applied to each of the recorded depths and a final, weighted depth may be computed.
20
DE102018000831A1
Klemmvorrichtungsanordnung mit Erkennungs- und Ausrichtungsfunktion
Publication/Patent Number: DE102018000831A1 Publication Date: 2019-08-01 Application Number: 102018000831 Filing Date: 2018-02-01 Inventor: Chen, Tony   Chuang, Eu-gene   Assignee: GMT GLOBAL INC.   IPC: G03B17/56 Abstract: Eine Klemmvorrichtungsanordnung mit Erkennungs- und Ausrichtungsfunktion umfasst primär eine an einem mechanischen Arm angebrachte Übertragungseinrichtung, eine in der Übertragungseinrichtung untergebrachte Kameralinsengruppe und eine mit der Übertragungseinrichtung verbundene Klemmeinrichtung, wobei die Übertragungseinrichtung die Klemmeinrichtung wahlweise in eine Klemmposition/Abstellposition oder eine Spurverfolgungsposition bewegt. Wenn sich die Klemmeinrichtung in der Klemmposition/Abstellposition befindet, ist die Kameraachse der Kameralinsengruppe koaxial auf die Klemmachse/Abstellachse der Klemmeinrichtung abgestimmt. Wenn die Klemmeinrichtung in die Spurverfolgungsposition bewegt wird, befindet sich die Klemmeinrichtung außerhalb des Sichtfelds der Kameralinsengruppe. Durch die von der Kameralinsengruppe aufgenommenen Bilder kann sowohl die Position eines zu klemmenden Werkstücks genau bestimmt als auch nach dem Klemmen die Montageposition des Werkstücks genau bestimmt werden, um dadurch die Genauigkeit der Klemmbetätigung/Abstellbetätigung der Klemmeinrichtung zu erhöhen.
Total 11 pages