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1
US10017364B2
Publication/Patent Number: US10017364B2
Publication date: 2018-07-10
Application number: 14/766,335
Filing date: 2014-02-06
Abstract: A traction winch for winching an elongated article having a high-tension end connectable to a load and low-tension end connectable to a storage device includes two or more rotatable drums arranged adjacent to each other with their rotational axes substantially parallel, each of them having a plurality of parallel, circumferential sheaves with groove, the sheaves being axially offset with respect to each other to allow wrapping of the elongated article around the sheaves of both drums in a spiral fashion. The sheaves includes fixed sheaves, stationary relative to their underlying drum, and rotatable sheaves, rotatable relative to their underlying drum. The majority of the rotatable sheaves of at least one of the drums is arranged adjacent to each other on a high load supporting side of the winch and the rotational velocity of at least one of the rotatable sheaves is reducible by means of at least one braking device. A traction winch for winching an elongated article having a high-tension end connectable to a load and low-tension end connectable to a storage device includes two or more rotatable drums arranged adjacent to each other with their rotational axes substantially parallel, each of ...more ...less
2
US9883790B2
Publication/Patent Number: US9883790B2
Publication date: 2018-02-06
Application number: 13/393,337
Filing date: 2010-08-05
Inventor: Wolter, Michael  
Abstract: A medical luminaire for photodynamic diagnosis. The medical luminaire including: a broad-band lamp for generating broad-band background light; a semiconductor lamp for generating short-wave excitation light, wherein the semiconductor lamp comprises a laser diode, the light from which is fed alternatively or additionally into a light path of the broad-band lamp, and a light fiber bundle for transporting the light, wherein the excitation light is transported in a partial bundle. A medical luminaire for photodynamic diagnosis. The medical luminaire including: a broad-band lamp for generating broad-band background light; a semiconductor lamp for generating short-wave excitation light, wherein the semiconductor lamp comprises a laser diode, the light from ...more ...less
3
US9890132B2
Publication/Patent Number: US9890132B2
Publication date: 2018-02-13
Application number: 14/914,378
Filing date: 2014-08-25
Abstract: Disclosed herein an efficient process for synthesis of benzofuran analogs having anti-inflammatory activity which comprises, Ru-catalyzed branched and linear selective alkylation of aroylbenzofurans formula-I with alpha, beta unsaturated esters of formula-II via C—H activation in presence of base, additives and organic solvent at suitable temperature to give high yield of desired linear alkylated benzofuran compounds of formula-III or branched alkylated benzofuran compounds of formula-IV or mixture thereof. Disclosed herein an efficient process for synthesis of benzofuran analogs having anti-inflammatory activity which comprises, Ru-catalyzed branched and linear selective alkylation of aroylbenzofurans formula-I with alpha, beta unsaturated esters of formula-II via C—H ...more ...less
4
US9890133B2
Publication/Patent Number: US9890133B2
Publication date: 2018-02-13
Application number: 15/189,771
Filing date: 2016-06-22
Abstract: Disclosed are novel indanone derivatives, pharmaceutically acceptable salts thereof or enantiomers, a preparation method thereof, and a pharmaceutical composition for the prevention or treatment of viral diseases, comprising the same as an active ingredient. The indanone derivatives have excellent inhibitory activity against picornaviruses including coxsackie-, entero-, echo-, Polio-, and rhinoviruses, as well as exhibiting low cytotoxicity, so that they can be useful as an active ingredient of a pharmaceutical composition for the prevention or treatment of viral diseases including poliomyelitis, paralysis, acute hemorrhagic conjunctivitis, viral meningitis, hand-foot-and-mouth disease, vesicular disease, hepatitis A, myositis, myocarditis, pancreatitis, diabetes, epidemic myalgia, encephalitis, cold, herpangina, foot-and-mouth disease, asthma, chronic obstructive pulmonary disease, pneumonia, sinusitis or otitis media. Disclosed are novel indanone derivatives, pharmaceutically acceptable salts thereof or enantiomers, a preparation method thereof, and a pharmaceutical composition for the prevention or treatment of viral diseases, comprising the same as an active ingredient. The indanone ...more ...less
5
US10017370B2
Publication/Patent Number: US10017370B2
Publication date: 2018-07-10
Application number: 15/200,112
Filing date: 2016-07-01
Abstract: A machine for filling containers, each container having a longitudinal axis, the machine comprising: a conveying device; at least one handling unit including a support device configured to receive and retain a container and at least one filling device selectively activated for feeding a pourable product into the container while the at least one handling unit travels along the transfer path; a pressurizing circuit; a decompression circuit; at least one actuating device; and a control unit configured to: control activation and deactivation of the at least one filling device and the at least one actuating device; control connection of the pressurization circuit and the decompression circuit with the container; and simultaneously maintain the at least one actuating device in an active state while the decompression circuit is in communication with the container so as to rotate the container about the longitudinal axis during decompression. A machine for filling containers, each container having a longitudinal axis, the machine comprising: a conveying device; at least one handling unit including a support device configured to receive and retain a container and at least one filling device selectively activated for ...more ...less
6
US9883793B2
Publication/Patent Number: US9883793B2
Publication date: 2018-02-06
Application number: 14/913,576
Filing date: 2014-08-22
Abstract: In some example implementations, there is provided a method. The method may include determining a probabilistic model representing threshold sensitivities across the visual field, the probabilistic model determined based on the data, the connection strengths, and the noise values. Related systems, methods, and articles of manufacture are also disclosed. In some implementations, the probabilistic model may include a continuous probability distribution. In some example implementations, there is provided a method. The method may include determining a probabilistic model representing threshold sensitivities across the visual field, the probabilistic model determined based on the data, the connection strengths, and the noise ...more ...less
7
US9883794B1
Publication/Patent Number: US9883794B1
Publication date: 2018-02-06
Application number: 14/819,046
Filing date: 2015-08-05
Abstract: A method and apparatus for administering eye tests to identify cone sensitivity loss associated with hereditary and acquired color vision loss which may be used for early detection, progress, treatment, and monitoring of eye conditions, traumatic brain injury, optic neuritis, systemic and neurological diseases including Glaucoma, Retinopathy, Age-Related Macular Degeneration, Multiple Sclerosis, Alzheimer's Disease, and Parkinson's Disease and retinal toxicity. Particularly, the method and apparatus disclosed uses a Cone Contrast Test (CCT) to test individuals for hereditary or acquired color vision loss associated with (a) early signs of potential disease/damage/toxicity in an effort to (i) provide opportunity for treatment, and (ii) prevent permanent eye damage, and (b) monitor progress and treatment of such disease/damage/toxicity. The system comprises a computer system including an input device and a display device, and the accuracy and repeatability of the testing is provided by repeated calibration using a colorimeter. A method and apparatus for administering eye tests to identify cone sensitivity loss associated with hereditary and acquired color vision loss which may be used for early detection, progress, treatment, and monitoring of eye conditions, traumatic brain injury, optic neuritis ...more ...less
8
US9883795B2
Publication/Patent Number: US9883795B2
Publication date: 2018-02-06
Application number: 14/662,079
Filing date: 2015-03-18
Inventor: Uchida, Hiroki  
Abstract: An optical coherence tomography apparatus includes a generation unit configured, based on interfering light produced by interfering a return beam and a reference beam of light emitted toward the object to be measured, to generate tomographic images of an object to be measured, an image processing unit configured to perform image processing for increasing image quality to at least one of the tomographic images generated by the generation unit, and a display control unit configured to display one of the tomographic images generated by the generation unit and then display the image on which the image processing is performed by the image processing unit on a display unit. An optical coherence tomography apparatus includes a generation unit configured, based on interfering light produced by interfering a return beam and a reference beam of light emitted toward the object to be measured, to generate tomographic images of an object to be measured ...more ...less
9
US10017375B2
Publication/Patent Number: US10017375B2
Publication date: 2018-07-10
Application number: 15/291,142
Filing date: 2016-10-12
Abstract: A method is provided for manufacturing a micromechanical component including a substrate and a cap connected to the substrate and together with the substrate enclosing a first cavity, a first pressure prevailing and a first gas mixture with a first chemical composition being enclosed in the first cavity. An access opening, connecting the first cavity to surroundings of the micromechanical component, is formed in the substrate or in the cap. The first pressure and/or the first chemical composition are adjusted in the first cavity. The access opening is sealed by introducing energy and heat into an absorbing part of the substrate or the cap with the aid of a laser. A recess is formed in a surface of the substrate or of the cap facing away from the first cavity in the area of the access opening for reducing local stresses occurring at a sealed access opening. A method is provided for manufacturing a micromechanical component including a substrate and a cap connected to the substrate and together with the substrate enclosing a first cavity, a first pressure prevailing and a first gas mixture with a first chemical composition being ...more ...less
10
US10017379B2
Publication/Patent Number: US10017379B2
Publication date: 2018-07-10
Application number: 15/492,193
Filing date: 2017-04-20
Abstract: According to an embodiment, a microelectromechanical systems (MEMS) transducer includes a substrate with a first cavity that passes through the substrate from a backside of the substrate. The MEMS transducer also includes a perforated first electrode plate overlying the first cavity on a topside of the substrate, a second electrode plate overlying the first cavity on the topside of the substrate and spaced apart from the perforated first electrode plate by a spacing region, and a gas sensitive material in the spacing region between the perforated first electrode plate and the second electrode plate. The gas sensitive material has an electrical property that is dependent on a concentration of a target gas. According to an embodiment, a microelectromechanical systems (MEMS) transducer includes a substrate with a first cavity that passes through the substrate from a backside of the substrate. The MEMS transducer also includes a perforated first electrode plate overlying the first ...more ...less
11
US10017380B1
Publication/Patent Number: US10017380B1
Publication date: 2018-07-10
Application number: 15/676,457
Filing date: 2017-08-14
Abstract: A micromechanical device that includes a first substrate, at least one first cavity, and a sealed inlet to the first cavity, the inlet extending through the first substrate. The inlet includes a laser-drilled first subsection and a plasma-etched second subsection, the plasma-etched second subsection having an opening to the first cavity, and the inlet in the first subsection being sealed by a molten seal made of molten mass of at least the first substrate. A combined laser drilling and plasma etching method for manufacturing micromechanical devices is also described. A micromechanical device that includes a first substrate, at least one first cavity, and a sealed inlet to the first cavity, the inlet extending through the first substrate. The inlet includes a laser-drilled first subsection and a plasma-etched second subsection, the ...more ...less
12
US9883803B2
Publication/Patent Number: US9883803B2
Publication date: 2018-02-06
Application number: 14/538,776
Filing date: 2014-11-11
Abstract: An apparatus for turbid sample measurement comprising a plurality of light sources for illuminating a turbid sample target area with non-spatial structured light, a projection system for illuminating the turbid sample target area with spatial structured light, a sensor for collecting light from the turbid sample target area, and a processor to analyze the data captured by the sensor to yield scattering and absorption coefficients of the turbid sample. A method comprises illuminating the sample with spatial structured light, collecting light reflected from the sample at a number of wavelengths, illuminating the sample with non-spatial structured light, collecting light reflected from the sample at a number of wavelengths, and combining the measurements of the collected light to obtain the optical properties of the sample and/or the concentration of absorbing or fluorescent molecules. The wavelengths of the spatial and non-spatial light sources are preferably different. An apparatus for turbid sample measurement comprising a plurality of light sources for illuminating a turbid sample target area with non-spatial structured light, a projection system for illuminating the turbid sample target area with spatial structured light, a sensor for ...more ...less
13
US10017382B2
Publication/Patent Number: US10017382B2
Publication date: 2018-07-10
Application number: 15/043,850
Filing date: 2016-02-15
Abstract: A method embodiment includes providing a micro-electromechanical (MEMS) wafer including a polysilicon layer having a first and a second portion. A carrier wafer is bonded to a first surface of the MEMS wafer. Bonding the carrier wafer creates a first cavity. A first surface of the first portion of the polysilicon layer is exposed to a pressure level of the first cavity. A cap wafer is bonded to a second surface of the MEMS wafer opposite the first surface of the MEMS wafer. The bonding the cap wafer creates a second cavity comprising the second portion of the polysilicon layer and a third cavity. A second surface of the first portion of the polysilicon layer is exposed to a pressure level of the third cavity. The first cavity or the third cavity is exposed to an ambient environment. A method embodiment includes providing a micro-electromechanical (MEMS) wafer including a polysilicon layer having a first and a second portion. A carrier wafer is bonded to a first surface of the MEMS wafer. Bonding the carrier wafer creates a first cavity. A first surface of ...more ...less
14
US9883805B2
Publication/Patent Number: US9883805B2
Publication date: 2018-02-06
Application number: 14/761,601
Filing date: 2013-02-04
Inventor: Amato, Aldo  
Assignee: Amato, Aldo
Abstract: The invention is a method for the aesthetic analysis of the teeth in the smile area, suited to facilitate the identification of aesthetic dental treatments and including: photographic examination of the patient's teeth; calibration of the images as a function of certain measures taken; consistency check of the data to detect and limit errors due to incorrect measurements; identification on the calibrated images of a defined set of reference points; automatic analysis and parametrization of the images with respect to the reference points; determination of possible treatments suited to achieve the desired aesthetic improvement; and display and/or print representation of the resulting possible treatments. The invention is a method for the aesthetic analysis of the teeth in the smile area, suited to facilitate the identification of aesthetic dental treatments and including: photographic examination of the patient's teeth; calibration of the images as a function of certain measures ...more ...less
15
US9890144B2
Publication/Patent Number: US9890144B2
Publication date: 2018-02-13
Application number: 14/750,794
Filing date: 2015-06-25
Abstract: Compounds and embodiments of a method for treating and/or preventing autoimmune diseases are disclosed. The method includes administering to a subject having an autoimmune disease, such as an inflammatory bowel disease, a therapeutically effective amount of a compound according to formula I wherein X and Y independently are O or NR1; each R1 is independently H or C1-C6 alkyl; ring A is aryl; each R2 independently is H, alkyl, alkoxy, amide, cyano, halo, haloalkyl, hydroxyalkyl, heteroalkyl, heterocyclyl, sulfonyl, sulfonamide, or two R2 groups, taken together with the atom or atoms to which they are attached, combine to form a 4-10 membered ring system; p is 0, 1, 2, 3, or 4; R3 and R4 independently are H or C1-C6 alkyl; and R5 is halo, cyano, or C1-C6 alkyl. Compounds and embodiments of a method for treating and/or preventing autoimmune diseases are disclosed. The method includes administering to a subject having an autoimmune disease, such as an inflammatory bowel disease, a therapeutically effective amount of a compound according ...more ...less