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1
US9493768B2
Translational enhancer-element dependent vector systems
Publication/Patent Number: US9493768B2 Publication Date: 2016-11-15 Application Number: 14/715,239 Filing Date: 2015-05-18 Inventor: Mauro, Vincent P.   Edelman, Gerald M.   Zhou, Wei   Assignee: The Scripps Research Institute   IPC: C12P21/00 Abstract: A translation enhancer-driven positive feedback vector system is disclosed which is designed to facilitate identification of a Translational Enhancer Element (TEE) and to provide a means for overexpression of gene products. The system exploits both transcriptional and translational approaches to control the expression levels of genes and/or gene products. Methods are also disclosed for screening libraries of random nucleotide sequences to identify translational elements and for overproduction of proteins, which have uses in both research and industrial environments.
2
US9493770B2
Method for identifying antibiotic targets by complemented sequencing
Publication/Patent Number: US9493770B2 Publication Date: 2016-11-15 Application Number: 14/071,618 Filing Date: 2013-11-04 Inventor: Williams, David Hugh   Turner, Arthur Keith   Assignee: DISCUVA LIMITED   IPC: C40B30/06 Abstract: Provided herein are methods, and related compositions for identifying a putative essential gene which serves as an antibiotic target in a bacterium, the method, in some embodiments, comprising (a) generating an antibiotic resistant mutant of the bacterium by a method comprising the step of selecting for growth in the presence of an antibiotic to produce an antibiotic resistant mutant clone (AbR mutant); (b) transforming the AbR mutant with one or more essential genes of the bacterium and a transposon which insertionally inactivates bacterial DNA to produce a pool of transposon mutants which are merodiploid for the one or more essential genes; (c) growing bacteria from the merodiploid pool in the presence of different amounts of the antibiotic to produce two or more test cultures; and (d) comparing the distribution of transposon insertions between the test cultures to identify a putative essential gene serving as a target of the antibiotic in the bacterium.
3
US9493772B2
Method for reducing expression of downregulated in renal cell carcinoma in malignant gliomas
Publication/Patent Number: US9493772B2 Publication Date: 2016-11-15 Application Number: 14/285,184 Filing Date: 2014-05-22 Inventor: Petrecca, Kevin   Damha, Masad   Deleavey, Glen   Assignee: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY   IPC: C12N15/11 Abstract: The present invention relates to novel compositions and therapeutic methods for the treatment of cancer, in particular malignant glioma. The compositions include antisense oligonucleotides or RNAs or vectors encoding them which reduce expression of downregulated in renal cell carcinoma (DRR) in tumor cells, and inhibit malignant glioma cell invasion.
4
US9493776B2
System for increasing gene expression and vector comprising the system
Publication/Patent Number: US9493776B2 Publication Date: 2016-11-15 Application Number: 13/510,719 Filing Date: 2010-11-19 Inventor: Kumon, Hiromi   Huh, Nam-ho   Sakaguchi, Masakiyo   Watanabe, Masami   Assignee: National University Corporation Okayama University   Momotaro-Gene Inc.   IPC: C12N15/86 Abstract: An object of the present invention is to provide a method for increasing the expression of foreign genes, in particular, using a promoter, an enhancer, and the like, and an expression cassette containing a promoter, an enhancer, and the like, by which gene expression can be increased. The purpose is achieved with the use of the gene expression cassette comprising a DNA construct containing a gene to be expressed and a poly A addition sequence that are located downstream of a 1st promoter, and further comprising an enhancer or a 2nd promoter ligated downstream of the DNA construct.
5
US9493780B2
Chloroplast transit peptide
Publication/Patent Number: US9493780B2 Publication Date: 2016-11-15 Application Number: 13/757,456 Filing Date: 2013-02-01 Inventor: Lira, Justin M.   Cicchillo, Robert M.   Yerkes, Carla N.   Robinson, Andrew E.   Assignee: Dow AgroSciences LLC   IPC: C12N9/10 Abstract: This disclosure concerns compositions and methods for targeting peptides, polypeptides, and proteins to plastids of plastid-containing cells. In some embodiments, the disclosure concerns chloroplast transit peptides that may direct a polypeptide to a plastid, and nucleic acid molecules encoding the same. In some embodiments, the disclosure concerns methods for producing a transgenic plant material (e.g., a transgenic plant) comprising a chloroplast transit peptide, as well as plant materials produced by such methods, and plant commodity products produced therefrom.
6
US9495342B2
System and method for automatically inserting correct escaping functions for field references in a multi-tenant computing environment
Publication/Patent Number: US9495342B2 Publication Date: 2016-11-15 Application Number: 14/019,395 Filing Date: 2013-09-05 Inventor: Lawrance, Steven   Assignee: salesforce.com, inc.   IPC: G06F17/00 Abstract: Methods and systems are provided for automatically correcting escaping functions in a module of page rendering code. The method includes: providing an HTML escaping schema and a script escaping schema; identifying a first character sequence having a first escaping function; determining whether the first character sequence is coded in HTML or coded as a scripted element; correcting the first escaping function using the HTML escaping schema if the first character sequence is coded in HTML; and correcting the first escaping function using the script escaping schema if the first character sequence is coded as a scripted element.
7
US9495347B2
Systems and methods for extracting table information from documents
Publication/Patent Number: US9495347B2 Publication Date: 2016-11-15 Application Number: 13/943,668 Filing Date: 2013-07-16 Inventor: Stadermann, Jan   Symons, Stephan   Thon, Ingo   Assignee: Recommind, Inc.   IPC: G06F17/00 Abstract: Systems and methods for extracting table information from documents are provided herein. Exemplary methods may include annotating a document with annotations that identify table cell data included therein, generating a candidate table for each of a plurality of table models using the annotated table cell data, scoring each of the candidate tables, selecting a highest scoring candidate table, and annotating the highest scoring table to produce a final table.
8
US9495350B2
System and method for determining expertise through speech analytics
Publication/Patent Number: US9495350B2 Publication Date: 2016-11-15 Application Number: 13/617,553 Filing Date: 2012-09-14 Inventor: John, Ajita   Sammon, Michael J.   Klemm, Reinhard   Seligmann, Doree Duncan   Assignee: Avaya Inc.   IPC: G06F17/27 Abstract: Systems, methods, and non-transitory computer-readable storage media for determining expertise through speech analytics. The system associates speakers with respective segments of an audio conversation to yield associated speaker segments. The system also identifies a number of times a speaker has spoken about a topic in the audio conversation by searching the associated speaker segments for a term associated with the topic. The system then ranks the speaker as an expert in the topic when the number of times the speaker has spoken about the topic in the audio conversation exceeds a threshold. The audio conversation can include a compilation of a plurality of audio conversations. Moreover, the system can tag the associated speaker segments having the term with keyword tags and match a respective segment from the associated speaker segments with the speaker, the respective segment having a keyword tag.
9
US9495352B1
Natural language determiner to identify functions of a device equal to a user manual
Publication/Patent Number: US9495352B1 Publication Date: 2016-11-15 Application Number: 13/625,784 Filing Date: 2012-09-24 Inventor: Smyros, Athena Ann   Smyros, Constantine John   Assignee: Smyros, Athena Ann   Smyros, Constantine John   IPC: G06F17/27 Abstract: Embodiments described herein of the natural language determiner (NLD) illustrate the ability to determine, at runtime, the conversion of natural language text into a computer-usable form. The natural language determiner's function is used to identify all functions of a device equal to a user manual for the device and displays at least one function of the device equal to the user manual for the device.
10
US9495355B2
Solving and answering arithmetic and algebraic problems using natural language processing
Publication/Patent Number: US9495355B2 Publication Date: 2016-11-15 Application Number: 14/472,554 Filing Date: 2014-08-29 Inventor: Mungi, Ashish   Mustafi, Joy   Assignee: International Business Machines Corporation   IPC: G06F17/27 Abstract: A method for solving and answering an arithmetic or algebraic problem using natural language processing (NLP) is provided. The method may include receiving an input statement associated with the arithmetic or algebraic problem. The method may also include determining whether each sentence within a plurality of sentences associated with the input statement is a well-formed sentence from a mathematical perspective. The method may further include converting each statement into a well-formed sentence based on the determining whether each sentence within a plurality of sentences associated with the input statement is a well-formed sentence from a mathematical perspective. Additionally, the method may include converting each well-formed sentence into a mathematical equation to form a set of equations. Also, the method may include solving the set of equations to compute a mathematical result. The method may include narrating the mathematical result in natural language.
11
US9495362B2
Fragmented video systems
Publication/Patent Number: US9495362B2 Publication Date: 2016-11-15 Application Number: 14/475,428 Filing Date: 2014-09-02 Inventor: Lee, Pui Shan Xanaz   Assignee: Lee, Pui Shan Xanaz   IPC: G06F17/28 Abstract: According to embodiments of the invention, systems, methods and devices are provided for a plurality of participants speaking different languages to participate in a singing event by using pre-determined song samples of different languages. In one embodiment, a system is provided that includes a storage that identifies songs by using samples from the song. The storage contains a song including both text and melody, wherein the song contains a plurality of versions of different languages. The system also includes devices allowing superiors and subordinates speaking different languages to sing at the same time. The collaboration may then be recorded and stored remotely via a cloud-based server.
12
US9494340B1
Solar module positioning system
Publication/Patent Number: US9494340B1 Publication Date: 2016-11-15 Application Number: 13/969,187 Filing Date: 2013-08-16 Inventor: O'neill, Andrew   Assignee: O'Neill, Andrew   IPC: G01C21/02 Abstract: A solar positioning system configured to position a body, such as, but not limited to, a solar module, perpendicular to incoming solar energy to maintain an optimal angle of incidence with efficacy is disclosed. The solar positioning system may include a support subsystem having a first mechanism for controlling rotational adjustments about a first axis and a second mechanism for controlling rotational adjustments about a second axis, thereby controlling pan and tilt adjustment. Positioning of the support subsystem may be controlled by a plurality of pyroelectric infrared sensors similarly oriented. A differential amplifier and a comparator may be coupled between the sensor subsystem and an integrated circuit to ignore brief flashes of light. The solar positioning system may also be used with a solar positioning control system to control the position of two or more solar modules, such as hundreds of solar modules in a solar farm.
13
US9494347B2
Refrigeration cycle device
Publication/Patent Number: US9494347B2 Publication Date: 2016-11-15 Application Number: 14/413,131 Filing Date: 2013-06-20 Inventor: Kayano, Kenta   Nishijima, Haruyuki   Yamada, Etsuhisa   Takano, Yoshiaki   Assignee: DENSO CORPORATION   IPC: F25B13/00 Abstract: In a heating mode, a refrigerant circuit is switched in which a refrigerant is decompressed by an ejector to flow into a gas-liquid separator, and a separated gas phase refrigerant is introduced into an intermediate-pressure suction port of a compressor and at the same time a separated liquid phase refrigerant flows to at least a second variable throttle valve, an interior evaporator, and a suction port of the compressor, in this order. In a cooling mode, a refrigerant circuit is switched in which the refrigerant flowing out of the interior condenser is decompressed by a first variable throttle valve through an exterior heat exchanger to flow into the gas-liquid separator, and a separated gas phase refrigerant is introduced into the intermediate-pressure suction port of the compressor, and at the same time a separated liquid phase refrigerant flows to the second variable throttle valve, the interior evaporator, and the suction port of the compressor, in this order.
14
US9494363B2
Air-conditioning apparatus
Publication/Patent Number: US9494363B2 Publication Date: 2016-11-15 Application Number: 13/822,365 Filing Date: 2010-10-12 Inventor: Yamashita, Koji   Assignee: MITSUBISHI ELELCTRIC CORPORATION   IPC: F25D29/00 Abstract: An air-conditioning apparatus uses a zeotropic refrigerant mixture, in which its saturated liquid refrigerant temperature is lower than the saturated gas refrigerant temperature under the same pressure condition, as the heat source side refrigerant. When one or some of a plurality of heat exchangers related to heat medium functions as an evaporator, the air-conditioning apparatus executes an anti-freezing control that prevents the heat medium from freezing by estimating occurrence of freezing of the heat medium on the basis of a value obtained by subtracting a freezing temperature correction value that is set as a positive value larger than zero from an evaporating temperature of the refrigerant in the heat exchanger related to heat medium.
15
US9494371B2
Pumped refrigerant cooling system with 1+1 to N+1 and built-in redundancy
Publication/Patent Number: US9494371B2 Publication Date: 2016-11-15 Application Number: 13/723,986 Filing Date: 2012-12-21 Inventor: Werner, Douglas E.   Hom, James   Lin, Tien-chih   Chow, Norman   Brewer, Richard G.   Leong, Brandon R.   Assignee: Liebert Corporation   IPC: F25B7/00 Abstract: A pumped refrigerant cooling system having cooling units with associated pumping units for providing working fluid to the cooling unit to enable cooling of a space. The pumped refrigerant cooling system also includes a redundant pumping unit which is activated when a primary pumping unit associated with a cooling unit becomes inactive. The primary pumping unit is deactivated in favor of the redundant pumping unit. Once the primary pumping unit is placed in a condition suitable for reactivation, the redundant pumping unit is deactivated, and the primary pumping unit is reactivated.
16
US9495283B2
System and method for server migration synchronization
Publication/Patent Number: US9495283B2 Publication Date: 2016-11-15 Application Number: 14/216,187 Filing Date: 2014-03-17 Inventor: Alger, James   Reza, Masood   Romanowski, Judy   Treger, Jerold R.   Wright, Lora L.   Assignee: III Holdings 1, LLC   IPC: G06F11/36 Abstract: A system and method for managing the migration of software components among test servers that form a distributed software test environment to ensure that the software components in each of the test servers represent a production environment except for software components being tested. The system further ensures that component changes rolled out into production are not overridden when multiple update requests are made for the same component.
17
US9495294B2
Enhancing data processing performance by cache management of fingerprint index
Publication/Patent Number: US9495294B2 Publication Date: 2016-11-15 Application Number: 14/747,192 Filing Date: 2015-06-23 Inventor: Hyde, Ii Joseph S.   Roy, Subhojit   Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION   IPC: G06F7/00 Abstract: Various embodiments for improving hash index key lookup caching performance in a computing environment are provided. In one embodiment, for a cached fingerprint map having a plurality of entries corresponding to a plurality of data fingerprints, reference count information is used to determine a length of time to retain the plurality of entries in cache. Those of the plurality of entries having a higher reference counts are retained longer than those having lower reference counts.
18
US9495298B2
Cache line crossing load techniques
Publication/Patent Number: US9495298B2 Publication Date: 2016-11-15 Application Number: 14/734,784 Filing Date: 2015-06-09 Inventor: Dooley, Miles R.   Hrusecky, David A.   Assignee: International Business Machines Corporation   IPC: G06F12/08 Abstract: A technique for handling an unaligned load operation includes detecting a cache line crossing load operation that is associated with a first cache line and a second cache line. In response to an cache including the first cache line but not including the second cache line, the second cache line is reloaded into the cache in a same set as the first cache line. In response to reloading the second cache line in the cache, a cache line crossing link indicator associated with the first cache line is asserted to indicate that both the first and second cache lines include portions of a desired data element.
19
US9495302B2
Virtualization of memory for programmable logic
Publication/Patent Number: US9495302B2 Publication Date: 2016-11-15 Application Number: 14/462,460 Filing Date: 2014-08-18 Inventor: Ahmad, Sagheer   Assignee: XILINX, INC.   IPC: G06F12/00 Abstract: A processing sub-system is configured to execute a program using a set of virtual memory addresses to reference memory locations for storage of variables of the program. A programmable logic sub-system is configured to implement a set of I/O circuits specified in a configuration data stream, each of the I/O circuits having a respective ID and configured to access one of the variables. A memory management circuit is configured to map the virtual memory addresses to physical memory addresses of a memory and map IDs to the physical address used to store the corresponding variables. A TLB is configured to receive a memory access request, from the I/O circuits, each request indicating an ID and provide, to the memory, a memory access request indicating the physical memory address that is mapped to the ID.
20
US9495306B1
Dynamic management of a processor state with transient cache memory
Publication/Patent Number: US9495306B1 Publication Date: 2016-11-15 Application Number: 15/010,686 Filing Date: 2016-01-29 Inventor: Bradbury, Jonathan D.   Greiner, Dan F.   Gschwind, Michael Karl   Jacobi, Christian   Manton, Younes   Saporito, Anthony   Shum, Chung-lung Kevin   Siu, Joran S. C.   Siegel, Timothy J.   Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION   IPC: G06F12/08 Abstract: According to some embodiments, a method for controlling a processor state with transient cache memory is described. The method may include identifying, via a processor, a memory section having a memory address, retrieving, via the processor, memory control information, and controlling the processor state by allowing a memory access to the transient cache memory based on the memory control information.
Total 500 pages