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No. Publication Number Title Publication/Patent Number Publication/Patent Number Publication Date Publication Date
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1 WO2012133111A1
SURFACE TREATMENT AGENT COMPOSITION FOR TIN-PLATED STEEL
Publication/Patent Number: WO2012133111A1 Publication Date: 2012-10-04 Application Number: 2012057348 Filing Date: 2012-03-22 Inventor: Matsukawa, Masahiko   Hirano, Tomio   Uchikawa, Miwa   Assignee: Nippon Paint Co., Ltd.   Matsukawa, Masahiko   HIRANO, TOMIO   UCHIKAWA, MIWA   IPC: B32B15/08 Abstract: The purpose of the present invention is to provide a surface treatment agent composition which contains aluminum as the coating film formation component and exhibits excellent properties for removing tin ions within a treatment bath when subjecting a tin-plated steel to electrolytic surface treatment The purpose of the present invention is to provide a surface treatment agent composition which contains aluminum as the coating film formation component and exhibits excellent properties for removing tin ions within a treatment bath when subjecting a tin-plated steel to ...More ...Less
2 WO2012133112A1
SURFACE TREATMENT AGENT COMPOSITION
Publication/Patent Number: WO2012133112A1 Publication Date: 2012-10-04 Application Number: 2012057349 Filing Date: 2012-03-22 Inventor: Matsukawa, Masahiko   Hirano, Tomio   Taya, Shinichi   Kurokawa, Wataru   Yoshimura, Kunihiro   Kanazawa, Seitaro   Hirotsu, Munemitsu   Uchikawa, Miwa   Taguchi, Naomi   Assignee: Nippon Paint Co., Ltd.   Toyo Kohan Co., Ltd.   Toyo Seikan Kaisha, Ltd.   Matsukawa, Masahiko   HIRANO, TOMIO   TAYA, SHINICHI   KUROKAWA, WATARU   YOSHIMURA, KUNIHIRO   KANAZAWA, SEITARO   HIROTSU, MUNEMITSU   UCHIKAWA, MIWA   TAGUCHI, NAOMI   IPC: B32B15/08 Abstract: The purpose of the present invention is to provided: a surface treatment agent composition for non-chromium steel sheets whereby it is possible to remove iron ions without reducing the amount of aluminum ions when subjecting the steel sheet to surface treatment by means of cathodic electrolysis using a surface treatment agent containing aluminum ions as the main component; and a method for producing a surface-treated steel sheet using such a composition. Another purpose of the present invention is to provide a surface-treated steel sheet exhibiting higher corrosion resistance than prior art The purpose of the present invention is to provided: a surface treatment agent composition for non-chromium steel sheets whereby it is possible to remove iron ions without reducing the amount of aluminum ions when subjecting the steel sheet to surface treatment by means of ...More ...Less
3 WO2007148835A1
AGENT FOR OVERCOMING RESISTANCE TO ANTI-CANCER AGENT
Publication/Patent Number: WO2007148835A1 Publication Date: 2007-12-27 Application Number: 2007063062 Filing Date: 2007-06-22 Inventor: Yamakawa, Tomio   Saito, Hikaru   Ishikawa, Toshihisa   Hirano, Masuharu   Assignee: Nippon Chemiphar Co., Ltd.   YAMAKAWA, TOMIO   SAITO, HIKARU   ISHIKAWA, TOSHIHISA   HIRANO, MASUHARU   IPC: A61K31/426 Abstract: An agent comprising
4 JP2006081861A
STAND FOR PLACING REAL FLOWER
Publication/Patent Number: JP2006081861A Publication Date: 2006-03-30 Application Number: 2004299377 Filing Date: 2004-09-14 Inventor: Hirano, Tomio   Assignee: HIRANO TOMIO   IPC: A47G7/04 Abstract: PROBLEM TO BE SOLVED: To provide a stand for placing a decoration in mid air among real flowers. SOLUTION: The stand is provided with leg rods by which the lower section of a stand for fixing a decoration by a fixing means such as a string is inserted and fixed in a container which contains an absorptive sponge PROBLEM TO BE SOLVED: To provide a stand for placing a decoration in mid air among real flowers. SOLUTION: The stand is provided with leg rods by which the lower section of a stand for fixing a decoration by a fixing means such as a string is inserted and fixed in a container ...More ...Less
5 WO2006051623A1
THERAPEUTIC AGENT FOR ANGIOSPASM CAUSED BY SUBARACHNOID HEMORRHAGE
Publication/Patent Number: WO2006051623A1 Publication Date: 2006-05-18 Application Number: 2005005068 Filing Date: 2005-03-15 Inventor: Hirano, Katsuya   Sasaki, Tomio   Maeda, Yoshihisa   Kanaide, Hideo   Kai, Yasutoshi   Assignee: Eisai Co., Ltd.   Kyushu University, National University Corporation   HIRANO, KATSUYA   SASAKI, TOMIO   MAEDA, YOSHIHISA   KANAIDE, HIDEO   KAI, YASUTOSHI   IPC: Abstract: A therapeutic agent for subarachnoid hemorrhage
6 WO2006051648A1
REMEDY FOR ANGIOSPASM ACCOMPANYING SUBARACHNOID HEMORRHAGE CONTIANING THROMBIN RECEPTOR ANTAGONIST AS THE ACTIVE INGREDIENT
Publication/Patent Number: WO2006051648A1 Publication Date: 2006-05-18 Application Number: 2005016568 Filing Date: 2005-09-02 Inventor: Hirano, Katsuya   Sasaki, Tomio   Maeda, Yoshihisa   Kanaide, Hideo   Kai, Yasutoshi   Assignee: Eisai Co., Ltd.   Kyushu University, National University Corporation   HIRANO, KATSUYA   SASAKI, TOMIO   MAEDA, YOSHIHISA   KANAIDE, HIDEO   KAI, YASUTOSHI   IPC: A61K31/4035 Abstract: A remedy for subarachnoid hemorrhage or a drug for improving prognosis of subarachnoid hemorrhage which contains a compound having a PAR1 inhibitory effect
7 WO2005089998A1
METHOD AND APPARATUS FOR FRICTION STIRRING-SPOT WELDING
Publication/Patent Number: WO2005089998A1 Publication Date: 2005-09-29 Application Number: 2005004602 Filing Date: 2005-03-16 Inventor: Hirano, Satoshi   Inagaki, Masahisa   Okamoto, Kazutaka   Aota, Kinya   Odakura, Tomio   Assignee: HIRANO, Satoshi   Hitachi, Ltd.   INAGAKI, MASAHISA   OKAMOTO, KAZUTAKA   AOTA, KINYA   ODAKURA, TOMIO   IPC: B23K20/12 Abstract: A method and an apparatus for friction stirring-spot welding capable of solving a problem in spot welding by FSW wherein welding strength tends to be lowered since an area to be metallic-bonded is limited to near the pin part of a welding tool. The method comprises the steps of pushing the welding tool (1) into a welded material (4) and tilting the rotating shaft of the welding tool (1) about a specified one point (13) to swing the tip portion of the welding tool (1) so as to increase a plastic flow area caused by the rotation of the tool. Thus A method and an apparatus for friction stirring-spot welding capable of solving a problem in spot welding by FSW wherein welding strength tends to be lowered since an area to be metallic-bonded is limited to near the pin part of a welding tool. The method comprises the steps of ...More ...Less
8 US2004074944A1
Apparatus and method for frictional stirring weld
Publication/Patent Number: US2004074944A1 Publication Date: 2004-04-22 Application Number: 10/372,324 Filing Date: 2003-02-25 Inventor: Okamoto, Kazutaka   Hirano, Satoshi   Inagaki, Masahisa   Odakura, Tomio   Assignee: Okamoto, Kazutaka   Hirano, Satoshi   Inagaki, Masahisa   Odakura, Tomio   IPC: B23K020/12 Abstract: In a frictional stirring weld apparatus for bonding elements with a rotary tool, a head is movable with respect to the elements to position and orient the rotary tool so that a pin of the rotary tool is aligned along a boundary between first surfaces and a shoulder of the rotary tool faces to second surfaces extending radially outward from the first surfaces, and to generate a relative movement between the rotary tool and the elements along the second surfaces, and a compensating member is capable of holding thereon the rotary tool, at least partially rotatable on the rotational axis with respect to the head to rotate the rotary tool, and supported on the head movably along the rotational axis with respect to the head so that a positional relationship between the rotary tool and a combination of the elements is adjustable in a direction parallel to the rotational axis. In a frictional stirring weld apparatus for bonding elements with a rotary tool, a head is movable with respect to the elements to position and orient the rotary tool so that a pin of the rotary tool is aligned along a boundary between first surfaces and a shoulder of the rotary ...More ...Less
9 US2004173663A1
Friction stir welding apparatus and method and processing apparatus and method
Publication/Patent Number: US2004173663A1 Publication Date: 2004-09-09 Application Number: 10/799,657 Filing Date: 2004-03-15 Inventor: Okamoto, Kazutaka   Hirano, Satoshi   Doi, Masayuki   Okamura, Hisanori   Inagaki, Masahisa   Odakura, Tomio   Tomobe, Masaru   Assignee: Okamoto, Kazutaka   Hirano, Satoshi   Doi, Masayuki   Okamura, Hisanori   Inagaki, Masahisa   Odakura, Tomio   Tomobe, Masaru   IPC: B23K020/12 Abstract: The invention provides a friction stir welding apparatus and method and a processing apparatus and method, which are not easily affected by deformations of a work being processed. The friction stir welding apparatus inserts a rotating tool into the work and moves the rotating tool relative to the work to join members of the work. The friction stir welding apparatus and method and the processing apparatus and method of the invention, the latter cutting or grinding the work with a rotating cutter or grindstone, comprises controlling a relative distance between the tool, cutter or grindstone and the work under the joining or processing operation or an insertion depth so that the load factor or electric current of a spindle motor for rotating the tool, cutter or grindstone is within a predetermined range, and a controller therefor. The invention provides a friction stir welding apparatus and method and a processing apparatus and method, which are not easily affected by deformations of a work being processed. The friction stir welding apparatus inserts a rotating tool into the work and moves the rotating ...More ...Less
10 US2003098337A1
Friction stir welding method and apparatus, and welded structure
Publication/Patent Number: US2003098337A1 Publication Date: 2003-05-29 Application Number: 10/342,305 Filing Date: 2003-01-15 Inventor: Hirano, Satoshi   Okamura, Hisanori   Aono, Yasuhisa   Okamoto, Kazutaka   Aota, Kinya   Odakura, Tomio   Hasshuu, Shinichi   Assignee: Hirano, Satoshi   Okamura, Hisanori   Aono, Yasuhisa   Okamoto, Kazutaka   Aota, Kinya   Odakura, Tomio   Hasshuu, Shinichi   IPC: B23K020/12 Abstract: It is an object of the present invention to provide a friction stir welding method and apparatus capable of maintaining a rotating tool and workpieces at a substantially constant geometrical relation for arbitrary curved surfaces having a three-dimensional shape, as well as a welded structure obtained thereby. The present invention resides in a friction stir welding method comprising joining workpieces while setting rotational angles of two rotational axes of a rotating tool which the two rotational axes are rotatable in intersecting directions or perpendicularly intersecting directions independently of rotation of the rotating tool, detecting a normal line direction with respect to joint surfaces of the workpieces and a tangential direction of a joint line, and joining the workpieces in three-dimensional directions while setting, on the basis of the detected normal line direction and tangential direction, an angle relative to a normal line direction, as well as a tangential direction, at a tip end of the rotating tool, and also resides in a friction stir welding apparatus using the said method. It is an object of the present invention to provide a friction stir welding method and apparatus capable of maintaining a rotating tool and workpieces at a substantially constant geometrical relation for arbitrary curved surfaces having a three-dimensional shape, as well as a ...More ...Less
11 US2003047584A1
Friction stir welding apparatus and method and processing apparatus and method
Publication/Patent Number: US2003047584A1 Publication Date: 2003-03-13 Application Number: 10/100,093 Filing Date: 2002-03-19 Inventor: Okamoto, Kazutaka   Hirano, Satoshi   Doi, Masayuki   Okamura, Hisanori   Inagaki, Masahisa   Odakura, Tomio   Tomobe, Masaru   Assignee: Okamoto, Kazutaka   Hirano, Satoshi   Doi, Masayuki   Okamura, Hisanori   Inagaki, Masahisa   Odakura, Tomio   Tomobe, Masaru   IPC: B23K020/12 Abstract: The invention provides a friction stir welding apparatus and method and a processing apparatus and method, which are not easily affected by deformations of a work being processed. The friction stir welding apparatus inserts a rotating tool into the work and moves the rotating tool relative to the work to join members of the work. The friction stir welding apparatus and method and the processing apparatus and method of the invention, the latter cutting or grinding the work with a rotating cutter or grindstone, comprises controlling a relative distance between the tool, cutter or grindstone and the work under the joining or processing operation or an insertion depth so that the load factor or electric current of a spindle motor for rotating the tool, cutter or grindstone is within a predetermined range, and a controller therefor. The invention provides a friction stir welding apparatus and method and a processing apparatus and method, which are not easily affected by deformations of a work being processed. The friction stir welding apparatus inserts a rotating tool into the work and moves the rotating ...More ...Less
12 US2003047590A1
Friction stir welding apparatus and method and processing apparatus and method
Publication/Patent Number: US2003047590A1 Publication Date: 2003-03-13 Application Number: 10/195,452 Filing Date: 2002-07-16 Inventor: Okamoto, Kazutaka   Hirano, Satoshi   Doi, Masayuki   Okamura, Hisanori   Inagaki, Masahisa   Odakura, Tomio   Tomobe, Masaru   Assignee: Okamoto, Kazutaka   Hirano, Satoshi   Doi, Masayuki   Okamura, Hisanori   Inagaki, Masahisa   Odakura, Tomio   Tomobe, Masaru   IPC: B23K035/12 Abstract: The invention provides a friction stir welding apparatus and method and a processing apparatus and method, which are not easily affected by deformations of a work being processed. The friction stir welding apparatus inserts a rotating tool into the work and moves the rotating tool relative to the work to join members of the work. The friction stir welding apparatus and method and the processing apparatus and method of the invention, the latter cutting or grinding the work with a rotating cutter or grindstone, comprises controlling a relative distance between the tool, cutter or grindstone and the work under the joining or processing operation or an insertion depth so that the load factor or electric current of a spindle motor for rotating the tool, cutter or grindstone is within a predetermined range, and a controller therefor. The invention provides a friction stir welding apparatus and method and a processing apparatus and method, which are not easily affected by deformations of a work being processed. The friction stir welding apparatus inserts a rotating tool into the work and moves the rotating ...More ...Less
13 US6566394B1
Salicylamide derivatives
Publication/Patent Number: US6566394B1 Publication Date: 2003-05-20 Application Number: 10/049,158 Filing Date: 2002-05-30 Inventor: Takeuchi, Tomio   Umezawa, Kazuo   To-e, Sakino   Matsumoto, Naoki   Sawa, Tsutomu   Yoshioka, Takeo   Agata, Naoki   Hirano, Shin-ichi   Isshiki, Kunio   Assignee: Takeuchi, Tomio   Umezawa, Kazuo   To-e, Sakino   Matsumoto, Naoki   Sawa, Tsutomu   Yoshioka, Takeo   Agata, Naoki   Hirano, Shin-ichi   Isshiki, Kunio   IPC: A61K31336 Abstract: Salicylamide derivatives represented by formulae (1a) and (1b); intermediates in the production thereof; a process for producing the same; and drugs containing the same as the active ingredient. The salicylamide derivatives represented by formulae (1a) and (1b) are useful as anti-inflammatory agents and immunosuppressive agents which exert an effect of inhibiting the activation of NF-&kgr;B with little side effects. Salicylamide derivatives represented by formulae (1a) and (1b); intermediates in the production thereof; a process for producing the same; and drugs containing the same as the active ingredient. The salicylamide derivatives represented by formulae (1a) and (1b) are useful as ...More ...Less
14 US6482379B1
Sodium-based dechlorinating agent and waste treatment equipment
Publication/Patent Number: US6482379B1 Publication Date: 2002-11-19 Application Number: 09/704,894 Filing Date: 2000-11-02 Inventor: Sugimoto, Tomio   Itaya, Masumi   Hirano, Yoshinao   Harada, Hiroaki   Hirano, Hachiro   Sakurai, Sigeru   Yoshida, Makoto   Tanaka, Masaharu   Assignee: Sugimoto, Tomio   Itaya, Masumi   Hirano, Yoshinao   Harada, Hiroaki   Hirano, Hachiro   Sakurai, Sigeru   Yoshida, Makoto   Tanaka, Masaharu   IPC: C01D742 Abstract: A sodium-based dechlorinating agent g is added to a flue gas G6; hydrogen chloride contained in this flue gas is removed as residue of dechlorination; the thus removed residue of dechlorination is dissolved by adding water i; water-insoluble constituents k are separated from the resulting aqueous solution j; and after adjusting pH of the aqueous solution 1 remaining after separation of the water-insoluble constituents k, mercury, dioxin and the like are removed and discharged. The sodium-based dechlorinating agent g is mixed with a hydrophilic anti-caking agent, with an angle of repose of 40° or more, a dispersibility of less than 50, and a floodability index value of less than 90. A mean particle diameter of sodium hydrogencarbonate is set within a range of from 2 &mgr;m to 30 &mgr;m. The hydrophilic anti-caking agent comprises silica, and is contained in an amount of 0.1 mass % or more in the sodium-based dechlorinating agent. Further, a mean particle diameter of the hydrophilic anti-caking agent is set within a range of from 0.001 &mgr;m to 1 &mgr;m. This permits inhibition of occurrence of a pressure drop and leakage in the filter cloth of the dust collector. A sodium-based dechlorinating agent g is added to a flue gas G6; hydrogen chloride contained in this flue gas is removed as residue of dechlorination; the thus removed residue of dechlorination is dissolved by adding water i; water-insoluble constituents k are separated from the ...More ...Less
15 US2002006372A1
Sodium-based dechlorinating agent and waste treatment equipment
Publication/Patent Number: US2002006372A1 Publication Date: 2002-01-17 Application Number: 09/888,527 Filing Date: 2001-06-25 Inventor: Sugimoto, Tomio   Itaya, Masumi   Hirano, Yoshinao   Harada, Hiroaki   Hirano, Hachiro   Sakurai, Shigeru   Yoshida, Makoto   Tanaka, Masaharu   Assignee: Sugimoto, Tomio   Itaya, Masumi   Hirano, Yoshinao   Harada, Hiroaki   Hirano, Hachiro   Sakurai, Shigeru   Yoshida, Makoto   Tanaka, Masaharu   IPC: B01D053/68 Abstract: A sodium-based dechlorinating agent g is added to a flue gas G6; hydrogen chloride contained in this flue gas is removed as residue of dechlorination; the thus removed residue of dechlorination is dissolved by adding water i; water-insoluble constituents k are separated from the resulting aqueous solution j; and after adjusting pH of the aqueous solution l remaining after separation of the water-insoluble constituents k, mercury, dioxin and the like are removed and discharged. The sodium-based dechlorinating agent g is mixed with a hydrophilic anti-caking agent, with an angle of repose of 40° or more, a dispersibility of less than 50, and a floodability index value of less than 90. A mean particle diameter of sodium hydrogencarbonate is set within a range of from 2 &mgr;m to 30 &mgr;m. The hydrophilic anti-caking agent comprises silica, and is contained in an amount of 0.1 mass % or more in the sodium-based dechlorinating agent. Further, a mean particle diameter of the hydrophilic anti-caking agent is set within a range of from 0.001 &mgr;m to 1 &mgr;m. This permits inhibition of occurrence of a pressure drop and leakage in the filter cloth of the dust collector. A sodium-based dechlorinating agent g is added to a flue gas G6; hydrogen chloride contained in this flue gas is removed as residue of dechlorination; the thus removed residue of dechlorination is dissolved by adding water i; water-insoluble constituents k are separated from the ...More ...Less
16 US2002145031A1
Friction stir welding method and apparatus, and welded structure
Publication/Patent Number: US2002145031A1 Publication Date: 2002-10-10 Application Number: 09/939,654 Filing Date: 2001-08-28 Inventor: Hirano, Satoshi   Okamura, Hisanori   Aono, Yasuhisa   Okamoto, Kazutaka   Aota, Kinya   Odakura, Tomio   Hasshuu, Shinichi   Assignee: Hirano, Satoshi   Okamura, Hisanori   Aono, Yasuhisa   Okamoto, Kazutaka   Aota, Kinya   Odakura, Tomio   Hasshuu, Shinichi   IPC: B23K020/12 Abstract: It is an object of the present invention to provide a friction stir welding method and apparatus capable of maintaining a rotating tool and workpieces at a substantially constant geometrical relation for arbitrary curved surfaces having a three-dimensional shape, as well as a welded structure obtained thereby. The present invention resides in a friction stir welding method comprising joining workpieces while setting rotational angles of two rotational axes of a rotating tool which the two rotational axes are rotatable in intersecting directions or perpendicularly intersecting directions independently of rotation of the rotating tool, detecting a normal line direction with respect to joint surfaces of the workpieces and a tangential direction of a joint line, and joining the workpieces in three-dimensional directions while setting, on the basis of the detected normal line direction and tangential direction, an angle relative to a normal line direction, as well as a tangential direction, at a tip end of the rotating tool, and also resides in a friction stir welding apparatus using the said method. It is an object of the present invention to provide a friction stir welding method and apparatus capable of maintaining a rotating tool and workpieces at a substantially constant geometrical relation for arbitrary curved surfaces having a three-dimensional shape, as well as a ...More ...Less
17 US2001049005A1
ANTIREFLECTION COATING
Publication/Patent Number: US2001049005A1 Publication Date: 2001-12-06 Application Number: 08/993,491 Filing Date: 1997-12-18 Inventor: Ikegaya, Tatsuo   Hirano, Tomio   Assignee: Ikegaya, Tatsuo   Hirano, Tomio   IPC: B32B003/30 Abstract: Antireflection coating on a substrate which is coated with a low refractive index layer having a specified refractive index which in turn is coated with a high refractive index layer having a higher refractive index than the low refractive index layer, is either characterized in that a roughened surface which scatters and reflects the incident light entered into the low refractive index layer in contact with the substrate is formed at the interface between the low refractive index layer and the substrate, or that a light-diffusing layer which scatters and reflects the incident light entered into the low refractive index layer in contact with the substrate is formed at the interface between the low refractive index layer and the substrate, or that a hard coating layer in contact with the low refractive index layer is formed by dispersing a light-diffusing material in the hard coating layer, which scatters and reflects the incident light entered into the low refractive index layer. Antireflection coating on a substrate which is coated with a low refractive index layer having a specified refractive index which in turn is coated with a high refractive index layer having a higher refractive index than the low refractive index layer, is either characterized in ...More ...Less
18 US2001033876A1
Resin molding machine and resin tablet feeding machine
Publication/Patent Number: US2001033876A1 Publication Date: 2001-10-25 Application Number: 09/838,240 Filing Date: 2001-04-20 Inventor: Hirano, Junji   Miyagawa, Tsutomu   Katsuie, Tomio   Miyashita, Yasuhiko   Assignee: Hirano, Junji   Miyagawa, Tsutomu   Katsuie, Tomio   Miyashita, Yasuhiko   IPC: B29C051/00 Abstract: The resin molding machine is capable of executing many functions and easily expanding and modifying the structure. In the resin molding machine, a loader and an unloader are moved on common rail sections so as to convey a work piece and a molded product. An additional rail unit has a rail section, on which the loader and the unloader can be moved. The additional rail unit is detachably attached between a work piece feeding unit and a product accommodating unit. The common rail sections and the rail section of the additional rail unit are disconnectably connected. The resin molding machine is capable of executing many functions and easily expanding and modifying the structure. In the resin molding machine, a loader and an unloader are moved on common rail sections so as to convey a work piece and a molded product. An additional rail unit ...More ...Less
19 WO0112588A1
SALICYLAMIDE DERIVATIVES
Publication/Patent Number: WO0112588A1 Publication Date: 2001-02-22 Application Number: 0005332 Filing Date: 2000-08-09 Inventor: Takeuchi, Tomio   Matsumoto, Naoki   Isshiki, Kunio   Umezawa, Kazuo   To-e, Sakino   Sawa, Tsutomu   Yoshioka, Takeo   Agata, Naoki   Hirano, Shin-ichi   Assignee: Takeuchi, Tomio   Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai   Mercian Corporation   Matsumoto, Naoki   ISSHIKI, KUNIO   UMEZAWA, KAZUO   TO-E, SAKINO   SAWA, TSUTOMU   YOSHIOKA, TAKEO   AGATA, NAOKI   HIRANO, SHIN-ICHI   IPC: A61P19/02 Abstract: Salicylamide derivatives represented by formulae (1a) and (1b); intermediates in the production thereof; a process for producing the same; and drugs containing the same as the active ingredient. The salicylamide derivatives represented by formulae (1a) and (1b) are useful as anti-inflammatory agents and immunosuppressive agents which exert an effect of inhibiting the activation of NF- kappa B with little side effects. Salicylamide derivatives represented by formulae (1a) and (1b); intermediates in the production thereof; a process for producing the same; and drugs containing the same as the active ingredient. The salicylamide derivatives represented by formulae (1a) and (1b) are useful as ...More ...Less
20 WO9748693A1
ISOCOUMARIN DERIVATIVES AND USE THEREOF IN DRUGS
Publication/Patent Number: WO9748693A1 Publication Date: 1997-12-24 Application Number: 9601657 Filing Date: 1996-06-17 Inventor: Takeuchi, Tomio   Matsumoto, Naoki   Ishizuka, Masaaki   Yoshioka, Takeo   Agata, Naoki   Hirano, Shin-ichi   Tone, Hiroshi   Kumagai, Hiroyuki   Mase, Toshiyuki   Iguchi, Hiroshi   Assignee: Takeuchi, Tomio   Mercian Corporation   Matsumoto, Naoki   Ishizuka, Masaaki   YOSHIOKA, TAKEO   AGATA, NAOKI   HIRANO, SHIN-ICHI   TONE, HIROSHI   KUMAGAI, HIROYUKI   MASE, TOSHIYUKI   IGUCHI, HIROSHI   IPC: A61K31/35 Abstract: Compounds represented by general formula (I) and medicinal compositions thereof