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1
US10183331B2
Publication/Patent Number: US10183331B2
Publication date: 2019-01-22
Application number: 14/897,877
Filing date: 2014-06-11
Abstract: A method manufactures a metal alloy part by spark plasma sintering. The method includes the simultaneous application, inside a die, of a uniaxial pressure and of an electric current to a powder component material that has the following composition: 42 to 49% aluminum, 0.05 to 1.5% boron, at least 0.2% of at least one element selected from tungsten, rhenium and zirconium, optionally 0 to 5% of one or more elements selected from chromium, niobium, molybdenum, silicon and carbon, the balance being titanium and the total of the elements without aluminum and titanium being between 0.25 and 12%. A method manufactures a metal alloy part by spark plasma sintering. The method includes the simultaneous application, inside a die, of a uniaxial pressure and of an electric current to a powder component material that has the following composition: 42 to 49% aluminum, 0.05 to ...more ...less
2
US10222678B2
Publication/Patent Number: US10222678B2
Publication date: 2019-03-05
Application number: 15/562,350
Filing date: 2016-03-23
Inventor: Acef, Mohand Ouali  
Abstract: According to an aspect, the present description concerns a frequency-tunable laser source comprising: a set of N elementary sources (101-k), each elementary source being suitable for emitting a beam at a given central frequency (fk); an optical coupler (12) for coupling the beams emitted by each of the elementary sources in order to form a multi-spectral incident beam (Bin) regrouping all the frequencies of the N elementary sources in a same optical beam; a beam splitter (15) for forming, from the incident beam (Bin), a first beam (B1) and a second beam (B2), each regrouping all the frequencies of the elementary sources; a first tunable filter (16) for selecting, from the first beam (B1), a third beam (B3) at a first frequency (Fj); a second tunable filter (17) for selecting, from the second beam (B2), a fourth beam (B4) at a second frequency (Fl); a nonlinear frequency doubling crystal (18) for generating, from the third beam at the first frequency (Fj), a fifth beam (B5) having a frequency (F2j) which is twice the first frequency; a nonlinear sum-frequency generation crystal (19) for generating, from the fifth beam coming from the nonlinear frequency doubling crystal and from the fourth beam at the second frequency (Fl), a beam (Bout) having a frequency (F2j+1) equal to the sum of twice the first frequency (F2j) and the second frequency (Fl). According to an aspect, the present description concerns a frequency-tunable laser source comprising: a set of N elementary sources (101-k), each elementary source being suitable for emitting a beam at a given central frequency (fk); an optical coupler (12) for coupling the ...more ...less
3
US10177368B2
Publication/Patent Number: US10177368B2
Publication date: 2019-01-08
Application number: 15/105,392
Filing date: 2014-12-17
Abstract: An anode compartment for rechargeable lithium or sodium batteries, including: a solid electrolyte; a collector deposited on the solid electrolyte; and an active material made of lithium metal or sodium metal which has been grown between the solid electrolyte and the collector in order to form an electrode made of lithium metal or sodium metal with the collector, in which the collector is made of an amorphous alloy. A method for manufacturing such an anode compartment and a battery including said anode compartment is also presented. An anode compartment for rechargeable lithium or sodium batteries, including: a solid electrolyte; a collector deposited on the solid electrolyte; and an active material made of lithium metal or sodium metal which has been grown between the solid electrolyte and the collector in ...more ...less
4
US10206867B2
Publication/Patent Number: US10206867B2
Publication date: 2019-02-19
Application number: 15/361,176
Filing date: 2016-11-25
Abstract: An alcoholic extract of aerial parts of Solidago virgaurea subsp. alpestris, the method of production thereof, a cosmetic or dermatological composition containing it, as well as cosmetic and dermatological uses thereof, notably in the treatment of signs of skin ageing.
5
US10184971B2
Publication/Patent Number: US10184971B2
Publication date: 2019-01-22
Application number: 15/320,092
Filing date: 2015-06-19
Abstract: Disclosed is a method for diagnosis by reflectometry of a bundle of power lines including an input point and a plurality of branches, including the following steps: inserting (S50) electric markers having different frequency characteristics onto the branches of the bundle; injecting (S52) a test signal into the bundle from the input point; receiving (S54) a set of reflected signals produced by reflections of the test signal in the branches; analyzing all the reflected signals by identifying the markers and by assigning (S56) each reflected signal to one of the branches according to the frequency characteristic of the marker inserted onto the branch; and identifying the presence/absence of a defect in the branch by comparing (S58) the reflected signal assigned to the branch with a reflected signal model obtained by modelling the reflection of the test signal in the branch in the absence of any defect in the branch. Disclosed is a method for diagnosis by reflectometry of a bundle of power lines including an input point and a plurality of branches, including the following steps: inserting (S50) electric markers having different frequency characteristics onto the branches of the bundle; ...more ...less
6
US10201536B2
Publication/Patent Number: US10201536B2
Publication date: 2019-02-12
Application number: 15/571,971
Filing date: 2016-05-12
Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of bacterial infections in patients suffering from cirrhosis. In particular, the present invention relates to a method of treating bacterial infection in a patient suffering from cirrhosis comprising administering to the patient a therapeutically effective amount of a TLR7 and/or TLR8 agonist. The present invention relates to methods and pharmaceutical compositions for the treatment of bacterial infections in patients suffering from cirrhosis. In particular, the present invention relates to a method of treating bacterial infection in a patient suffering from cirrhosis ...more ...less
7
US10246548B2
Publication/Patent Number: US10246548B2
Publication date: 2019-04-02
Application number: 15/533,648
Filing date: 2015-12-17
Abstract: The present invention relates to a composition comprising a polymeric network having at least one unit of formula (I), (II), and/or (III); wherein the composition is obtained by contacting at least one compound A comprising at least two functions selected from the group of function of formula —X—C(═O)—CHR1-C(═O)—R2, —C(═O)—C≡C—R2; or —C(═O)—CR1═CR2—NR4R5; wherein at least 25% by weight of compounds A have a functionality ≤5, with % by weight relative to the total weight of compounds A; with at least one compound B comprising at least one —NH2, or —NH3+ groups; wherein X, R1, R2, R3, R4, R5, L1 and L2 have the same meaning as that defined in the claims. The present invention also relates to a compound comprising at least two units and at most 5 units of formula (I), (II), and/or (III), described hereinabove. The present invention also relates to processes for preparing the composition and the compounds, to material, articles, and polymers comprising or using the compositions and compounds, and the use thereof. The present invention relates to a composition comprising a polymeric network having at least one unit of formula (I), (II), and/or (III); wherein the composition is obtained by contacting at least one compound A comprising at least two functions selected from the group ...more ...less
8
US10173954B2
Publication/Patent Number: US10173954B2
Publication date: 2019-01-08
Application number: 15/598,400
Filing date: 2017-05-18
Abstract: The present invention relates to a process for hydroxylation of a compound of formula (I) by reacting the compound of formula (I) with an oxidizing agent, in the presence of a titanium silicalite zeolite prepared by crystallization preceded by a maturing step. The present invention also relates to a titanium silicalite zeolite and to the process for preparing same. The present invention relates to a process for hydroxylation of a compound of formula (I) by reacting the compound of formula (I) with an oxidizing agent, in the presence of a titanium silicalite zeolite prepared by crystallization preceded by a maturing step. The present ...more ...less
9
US10172527B2
Publication/Patent Number: US10172527B2
Publication date: 2019-01-08
Application number: 12/533,546
Filing date: 2009-07-31
Abstract: Method for measuring a physical parameter in soft tissues of a mammal, in which a mechanical shear wave is propagated through the soft tissues and observation of the propagation leads to determine values of a shear wave propagation parameter. The physical parameter is computed on the basis of these values. Method for measuring a physical parameter in soft tissues of a mammal, in which a mechanical shear wave is propagated through the soft tissues and observation of the propagation leads to determine values of a shear wave propagation parameter. The physical parameter is computed ...more ...less
10
US10196683B2
Publication/Patent Number: US10196683B2
Publication date: 2019-02-05
Application number: 15/570,070
Filing date: 2016-05-04
Abstract: The present invention relates to a method of preparation of substrates for nucleic acid sequencing reactions. More specifically, the present invention provides a new method of preparing hairpins using force-induced strand invasion. Hairpins prepared by this method and methods of nucleic acid analysis using these hairpins are also part of the present invention. The present invention relates to a method of preparation of substrates for nucleic acid sequencing reactions. More specifically, the present invention provides a new method of preparing hairpins using force-induced strand invasion. Hairpins prepared by this method and methods of ...more ...less
11
US10209505B2
Publication/Patent Number: US10209505B2
Publication date: 2019-02-19
Application number: 15/897,335
Filing date: 2018-02-15
Abstract: The invention relates to an optical device for measuring the position of an object along a first axis, the object being subjected to light radiations emitted by a light source. The optical device comprises: an imaging system comprising an objective for collecting light radiations diffused by the object, the imaging system having an optical axis extending parallel to the first axis; a transmission mask having at least a first aperture and a second aperture, the first aperture and second aperture being spaced from each other along a second axis, perpendicular to the first axis, the transmission mask being arranged so as to let a first part of the radiations and a second part of the radiations which are diffused by the object pass through the first aperture and the second aperture respectively, while blocking a part of the radiations emitted by the light source which is not diffused by the object; and a detector adapted for generating an image including a first spot and a second spot representative of the first part and second part of the radiations impacting the detector plane, wherein variation of the position of the object relative to the object plane of the imaging system along the first axis causes variation of a position of the first spot and of the second spot relative to each other along the second axis. The invention relates to an optical device for measuring the position of an object along a first axis, the object being subjected to light radiations emitted by a light source. The optical device comprises: an imaging system comprising an objective for collecting light ...more ...less
12
US9951286B2
Publication/Patent Number: US9951286B2
Publication date: 2018-04-24
Application number: 15/304,760
Filing date: 2015-04-17
Abstract: The invention relates to a material consisting of a preparation made from a mixture of ferrocene and an inert flameproof material such as plaster, the material being presented in the form of granules and being suitable for spreading over a hydrocarbon fire in a simple and rapid manner such that, under the effect of the heat from the fire, the ferrocene contained in the granulated material is diffused progressively and homogeneously in a vapor phase over the base of the flames, so as to optimize the combustion of the hydrocarbon and to reduce the emission of smoke and unwanted particles. The invention relates to a material consisting of a preparation made from a mixture of ferrocene and an inert flameproof material such as plaster, the material being presented in the form of granules and being suitable for spreading over a hydrocarbon fire in a simple and rapid ...more ...less
13
US10162246B2
Publication/Patent Number: US10162246B2
Publication date: 2018-12-25
Application number: 15/112,567
Filing date: 2015-01-19
Abstract: The invention relates to a method for manufacturing mirrors with saturable semiconducting absorptive material, which includes: depositing a saturable semiconducting absorptive material (205) onto a growth substrate (200) in order to form a structure; depositing at least one metal layer onto the structure such as to form a first mirror (211); and depositing a heat-conductive substrate (212) onto the metal layer by electrodeposition through an electrically insulating mask (312), allowing the selective deposition of the thermally conductive substrate, in order to predefine the perimeter of the mirrors with saturable semiconducting absorptive material. The invention relates to a method for manufacturing mirrors with saturable semiconducting absorptive material, which includes: depositing a saturable semiconducting absorptive material (205) onto a growth substrate (200) in order to form a structure; depositing at least one ...more ...less
14
US9923106B2
Publication/Patent Number: US9923106B2
Publication date: 2018-03-20
Application number: 14/892,708
Filing date: 2014-05-12
Abstract: A method for fabricating a photosensitive device, comprising: a first step of preparing, on a substrate, at least a first photosensitive portion, active within a range of wavelengths, the first portion being surrounded by a second portion that is inactive. A material, covering the first portion, is selectively arranged into a hydrophilic layer by an electrochemical process. The second portion comprises a hydrophobic material on an upper surface opposite the substrate. The method further comprises the following steps: spraying on the upper surfaces of the first and second portions a liquid comprising a transparent material, and forming a converging lens containing the material, above the first portion. A method for fabricating a photosensitive device, comprising: a first step of preparing, on a substrate, at least a first photosensitive portion, active within a range of wavelengths, the first portion being surrounded by a second portion that is inactive. A material, covering ...more ...less
15
US9952321B2
Publication/Patent Number: US9952321B2
Publication date: 2018-04-24
Application number: 11/910,491
Filing date: 2006-03-30
Abstract: The inventive imaging method consists in generating a mechanical wave having shearing and compressional components in a viscoelastic medium and in determining the movement parameter of said viscoelastic medium at different points during the propagation of said mechanical wave. Said method comprises a correction stage when the movement parameter is processed for eliminating errors caused by the compressional component of the mechanical wave. The inventive imaging method consists in generating a mechanical wave having shearing and compressional components in a viscoelastic medium and in determining the movement parameter of said viscoelastic medium at different points during the propagation of said mechanical wave ...more ...less
16
US9963669B2
Publication/Patent Number: US9963669B2
Publication date: 2018-05-08
Application number: 15/101,255
Filing date: 2014-12-01
Abstract: The invention concerns a facility for coupling a bioreactor for culturing bio-organisms, in dynamic mode, with at least one device for physicochemically analyzing a fluid from this bioreactor or collecting samples of this fluid, the device being equipped with a pump and an injector, the bioreactor being equipped with means for supplying culture medium and xenobiotic(s). The facility is remarkable in that the bioreactor is connected to a closed perfusion loop provided with a pump, fitted with a sampling loop and in that the facility comprises: a device for injecting a cleaning product into said sampling loop, two six-way valves, the first valve being connected to the closed perfusion loop, to the sampling loop and to a cleaning loop, the second valve being connected to the cleaning loop and an injection loop that connects the injector to at least one of the devices. The invention concerns a facility for coupling a bioreactor for culturing bio-organisms, in dynamic mode, with at least one device for physicochemically analyzing a fluid from this bioreactor or collecting samples of this fluid, the device being equipped with a pump and an ...more ...less
17
US10119112B2
Publication/Patent Number: US10119112B2
Publication date: 2018-11-06
Application number: 13/582,068
Filing date: 2011-03-02
Abstract: The present invention relates to a unit (1) comprising a microsystem (150) and at least one set of interface connections (16) for the microsystem (150); the microsystem (150) comprising a bottom plate (152) bearing the impression of at least one microstructured dynamic cell culture chamber (15), and a top plate (151), characterized in that the at least one microstructured chamber (15) is fluidically connected at inlet and/or at outlet by a set of connections (16) inserted removably into a hole in the upper plate (151). The present invention also relates to a dynamic cell culture system to this effect. The present invention relates to a unit (1) comprising a microsystem (150) and at least one set of interface connections (16) for the microsystem (150); the microsystem (150) comprising a bottom plate (152) bearing the impression of at least one microstructured dynamic cell ...more ...less