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1 US2019359574A1
PROCESS FOR THE PREPARATION OF QUINOLONE BASED COMPOUNDS
Publication/Patent Number: US2019359574A1 Publication Date: 2019-11-28 Application Number: 16/421,671 Filing Date: 2019-05-24 Inventor: Desai, Ranjit C.   Sharma, Rajiv   Pandya, Vrajesh   Shah, Kalpesh   Patel, Sunil   Chauhan, Rakesh   Nair, Ranjeet   Joshi, Vivek   Patel, Manoj   Shukla, Mrigendra   Assignee: CADILA HEALTHCARE LIMITED   IPC: C07D215/58 Abstract: The present invention relates to an improved process for the preparation of quinolone based compounds of general formula (I) using intermediate compound of general formula (XII). Invention also provides an improved process for the preparation of compound of formula (I-a) using intermediate compound of formula (XII-a) and some novel impurities generated during process. Compounds prepared using this process can be used to treat anemia. The present invention relates to an improved process for the preparation of quinolone based compounds of general formula (I) using intermediate compound of general formula (XII). Invention also provides an improved process for the preparation of compound of formula (I-a) using ...More ...Less
2 US10049030B2
System and method for test output evaluation of a JAVA component
Publication/Patent Number: US10049030B2 Publication Date: 2018-08-14 Application Number: 13/969,456 Filing Date: 2013-08-16 Inventor: Bansal, Shruti   Shukla, Rakesh   Assignee: Infosys Limited   IPC: G06F11/36 Abstract: A method and a system for test output evaluation of a JAVA component. The java component and reference classes are received and non-private members of the Java component are identified using JAVA reflection API and the reference classes. An API structure comprising public members is extracted from the non-private members. Behavior checking expressions are received and selected corresponding to the public members. A Java source code comprising wrapper methods wherein the wrapper method corresponds to the one or more public members and a test output evaluation method comprising the behavior checking expressions is generated. The test output evaluation of the JAVA component is performed using the test output evaluation method over the generated Java source code. A method and a system for test output evaluation of a JAVA component. The java component and reference classes are received and non-private members of the Java component are identified using JAVA reflection API and the reference classes. An API structure comprising public ...More ...Less
3 US10102186B2
System for and method of providing a user interface for a computer-based software application
Publication/Patent Number: US10102186B2 Publication Date: 2018-10-16 Application Number: 14/171,665 Filing Date: 2014-02-03 Inventor: Buttner, Karl   Orenchuk, Erich E.   Shukla, Rakesh   Assignee: KOFAX, INC.   IPC: G06F3/0481 Abstract: A system for providing a graphical interface to a user includes a server platform and an operating system and application software running thereon. The system includes a client device capable of running a standard web browser that accesses the software application on the server platform for displaying information to the user in a display area on the client device. The web browser displays the information without requiring additional software to be installed, downloaded or run on the client device, and without requiring a scripting language to be enabled in the web browser on the client. The application software facilitates user manipulation of unstructured data in the display area for detailed inspection, and facilitates the user selectively causing to display annotations within the display area. The application software facilitates the user inserting annotations within the display area, thereby causing an action to occur in this system or an external system. A system for providing a graphical interface to a user includes a server platform and an operating system and application software running thereon. The system includes a client device capable of running a standard web browser that accesses the software application on the server ...More ...Less
4 EP3200770A1
A FORMULATION USEFUL FOR DELIVERY OF NEURO PROTECTING AGENT
Publication/Patent Number: EP3200770A1 Publication Date: 2017-08-09 Application Number: 15787314.2 Filing Date: 2015-09-29 Inventor: Dwivedi, Anil Kumar   Khandelwal, Kiran   Sangwan, Rajender Singh   Shukla, Rakesh   Gayen, Jiaur Rahaman   Sarika   Sharma, Sharad   Ahmad, Hafsa   Bhaduaria, Smrati   Gaur, Suresh Pratap Singh   Sangwan, Neelam Singh   Rath, Srikanta Kumar   Bhosale, Vivek Vidyadhar   Assignee: Council of Scientific and Industrial Research   IPC: A61P9/10
5 AU2015326378A1
A formulation useful for delivery of neuro protecting agent
Publication/Patent Number: AU2015326378A1 Publication Date: 2016-08-18 Application Number: 2015326378 Filing Date: 2015-09-29 Inventor: Sharma, Sharad   Dwivedi, Anil Kumar   Rath, Srikanta Kumar   Ahmad, Hafsa   Bhaduaria, Smrati   Bhosale, Vivek Vidyadhar   Gaur, Suresh Pratap Singh   Khandelwal, Kiran   Sangwan, Neelam Singh   Sarika   Sangwan, Rajender Singh   Gayen, Jiaur Rahaman   Shukla, Rakesh   Assignee: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH   IPC: A61K9/127 Abstract: The present invention relates to a formulation useful for delivery of neuro protecting agent. It also demonstrates and discloses a novel delivery system for an extract of a new chemotype of Withania sonmifera (NMITLI118RT+) for neuro- protection against cerebral stroke (signifies concentrated aqueous ethanolic extract of roots of NMITLI-118 The present invention relates to a formulation useful for delivery of neuro protecting agent. It also demonstrates and discloses a novel delivery system for an extract of a new chemotype of Withania sonmifera (NMITLI118RT+) for neuro- protection against cerebral stroke ...More ...Less
6 WO2016051424A1
A FORMULATION USEFUL FOR DELIVERY OF NEURO PROTECTING AGENT
Publication/Patent Number: WO2016051424A1 Publication Date: 2016-04-07 Application Number: 2015050124 Filing Date: 2015-09-29 Inventor: Dwivedi, Anil Kumar   Rath, Srikanta Kumar   Shukla, Rakesh   Gayen, Jiaur Rahaman   Sharma, Sharad   Bhosale, Vivek Vidyadhar   Sarika   Khandelwal, Kiran   Gaur, Suresh Pratap Singh   Sangwan, Neelam Singh   Bhaduaria, Smrati   Sangwan, Rajender Singh   Ahmad, Hafsa   Assignee: Council of Scientific & Industrial Research   IPC: A61K9/127 Abstract: The present invention relates to a formulation useful for delivery of neuro protecting agent. It also demonstrates and discloses a novel delivery system for an extract of a new chemotype of Withania sonmifera (NMITLI118RT+) for neuro- protection against cerebral stroke (signifies concentrated aqueous ethanolic extract of roots of NMITLI-118 The present invention relates to a formulation useful for delivery of neuro protecting agent. It also demonstrates and discloses a novel delivery system for an extract of a new chemotype of Withania sonmifera (NMITLI118RT+) for neuro- protection against cerebral stroke ...More ...Less
7 WO2016051424A4
A FORMULATION USEFUL FOR DELIVERY OF NEURO PROTECTING AGENT
Publication/Patent Number: WO2016051424A4 Publication Date: 2016-05-19 Application Number: 2015050124 Filing Date: 2015-09-29 Inventor: Dwivedi, Anil Kumar   Rath, Srikanta Kumar   Shukla, Rakesh   Gayen, Jiaur Rahaman   Sharma, Sharad   Bhosale, Vivek Vidyadhar   Sarika   Khandelwal, Kiran   Gaur, Suresh Pratap Singh   Sangwan, Neelam Singh   Bhaduaria, Smrati   Sangwan, Rajender Singh   Ahmad, Hafsa   Assignee: Council of Scientific & Industrial Research   IPC: A61K9/127 Abstract: The present invention relates to a formulation useful for delivery of neuro protecting agent. It also demonstrates and discloses a novel delivery system for an extract of a new chemotype of Withania sonmifera (NMITLI118RT+) for neuro- protection against cerebral stroke (signifies concentrated aqueous ethanolic extract of roots of NMITLI-118 The present invention relates to a formulation useful for delivery of neuro protecting agent. It also demonstrates and discloses a novel delivery system for an extract of a new chemotype of Withania sonmifera (NMITLI118RT+) for neuro- protection against cerebral stroke ...More ...Less
8 EP2675790B1
SUBSTITUTED 1, 2, 3, 4-TETRAHYDROQUINOLIN-7-YL CARBAMATES AS ACETYLCHOLINESTERASE INHIBITORS FOR TREATMENT OF ALZHEIMER'S DISEASE
Publication/Patent Number: EP2675790B1 Publication Date: 2015-11-18 Application Number: 12706943.3 Filing Date: 2012-01-24 Inventor: Roy, Kuldeep Kumar   Nath, Chandishwar   Shukla, Rakesh   Saxena, Anil Kumar   Tota, Santoshkumar   Assignee: Council of Scientific & Industrial Research   IPC: A61P25/00
9 US8946261B2
Substituted 1, 2, 3, 4-tetrahydroquinolin-7-yl carbamates as acetylcholinesterase inhibitors for treatment of Alzheimer's disease
Publication/Patent Number: US8946261B2 Publication Date: 2015-02-03 Application Number: 13/984,998 Filing Date: 2012-01-24 Inventor: Roy, Kuldeep Kumar   Tota, Santoshkumar   Nath, Chandishwar   Shukla, Rakesh   Saxena, Anil Kumar   Assignee: Council of Scientific & Industrial Research   IPC: C07D215/20 Abstract: The present invention relates to novel substituted 1,2,3,4-tetrahydroquinolin-7-yl carbamates, their preparation, and use as therapeutic agents, particularly in the prevention or treatment of neurodegenerative or Alzheimer's disease, or senile dementia, or memory disturbances, and more particularly to the prevention, treatment and amelioration of Alzheimer's disease with the novel substituted 1,2,3,4-tetrahydroquinolin-7-yl carbamates, which act as inhibitors of central cholinesterase enzymes, particularly acetylcholinesterase (AChE) following the indirect cholinomimetic pathway. The present invention particularly relates to compounds of formula A: Formula A wherein R1=alkyl, aryl, substituted aryl; R2=H, methyl; R3=H, alkyl, alkenyl, alkynyl, aralkyl, substituted aralkyl, aryl, heteroaryl. The present invention relates to novel substituted 1,2,3,4-tetrahydroquinolin-7-yl carbamates, their preparation, and use as therapeutic agents, particularly in the prevention or treatment of neurodegenerative or Alzheimer's disease, or senile dementia, or memory disturbances ...More ...Less
10 US2014082591A1
SYSTEM AND METHOD FOR TEST OUTPUT EVALUATION OF A JAVA COMPONENT
Publication/Patent Number: US2014082591A1 Publication Date: 2014-03-20 Application Number: 13/969,456 Filing Date: 2013-08-16 Inventor: Shukla, Rakesh   Bansal, Shruti   Assignee: Infosys Limited   IPC: G06F11/36 Abstract: A method and a system for test output evaluation of a JAVA component. The java component and reference classes are received and non-private members of the Java component are identified using JAVA reflection API and the reference classes. An API structure comprising public members is extracted from the non-private members. Behavior checking expressions are received and selected corresponding to the public members. A Java source code comprising wrapper methods wherein the wrapper method corresponds to the one or more public members and a test output evaluation method comprising the behavior checking expressions is generated. The test output evaluation of the JAVA component is performed using the test output evaluation method over the generated Java source code. A method and a system for test output evaluation of a JAVA component. The java component and reference classes are received and non-private members of the Java component are identified using JAVA reflection API and the reference classes. An API structure comprising public ...More ...Less
11 US2014201612A1
SYSTEM FOR AND METHOD OF PROVIDING A USER INTERFACE FOR A COMPUTER-BASED SOFTWARE APPLICATION
Publication/Patent Number: US2014201612A1 Publication Date: 2014-07-17 Application Number: 14/171,665 Filing Date: 2014-02-03 Inventor: Buttner, Karl   Orenchuk, Erich E.   Shukla, Rakesh   Assignee: Kofax, Inc.   IPC: G06F17/22 Abstract: A system for providing a graphical interface to a user includes a server platform and an operating system and application software running thereon. The system includes a client device capable of running a standard web browser that accesses the software application on the server platform for displaying information to the user in a display area on the client device. The web browser displays the information without requiring additional software to be installed, downloaded or run on the client device, and without requiring a scripting language to be enabled in the web browser on the client. The application software facilitates user manipulation of unstructured data in the display area for detailed inspection, and facilitates the user selectively causing to display annotations within the display area. The application software facilitates the user inserting annotations within the display area, thereby causing an action to occur in this system or an external system. A system for providing a graphical interface to a user includes a server platform and an operating system and application software running thereon. The system includes a client device capable of running a standard web browser that accesses the software application on the server ...More ...Less
12 US8677249B2
System for and method of providing a user interface for a computer-based software application
Publication/Patent Number: US8677249B2 Publication Date: 2014-03-18 Application Number: 12/331,875 Filing Date: 2008-12-10 Inventor: Büttner, Karl   Orenchuk, Erich E.   Shukla, Rakesh   Assignee: Kofax, Inc.   IPC: G06F17/00 Abstract: A system for providing a graphical interface to a user includes a server platform and an operating system and application software running thereon. The system includes a client device capable of running a standard web browser that accesses the software application on the server platform for displaying information to the user in a display area on the client device. The web browser displays the information without requiring additional software to be installed, downloaded or run on the client device, and without requiring a scripting language to be enabled in the web browser on the client. The application software facilitates user manipulation of unstructured data in the display area for detailed inspection, and facilitates the user selectively causing to display annotations within the display area. The application software facilitates the user inserting annotations within the display area, thereby causing an action to occur in this system or an external system. A system for providing a graphical interface to a user includes a server platform and an operating system and application software running thereon. The system includes a client device capable of running a standard web browser that accesses the software application on the server ...More ...Less
13 TWI386817B
System for and method of providing a user interface for a computer-based software application
Publication/Patent Number: TWI386817B Publication Date: 2013-02-21 Application Number: 96118505 Filing Date: 2007-05-24 Inventor: Orenchuk, Erich E   Shukla, Rakesh   Assignee: KOFAX, INC.   IPC: G06F3/048 Abstract: A system for providing a graphical interface to a user includes a server platform and an operating system and application software running thereon. The system further includes a client device capable of running a standard web browser that accesses the application software on the server platform for displaying information to the user in a display area on the client device. The standard web browser displays the information without requiring additional software to be installed or downloaded or run on the client device A system for providing a graphical interface to a user includes a server platform and an operating system and application software running thereon. The system further includes a client device capable of running a standard web browser that accesses the application software on the ...More ...Less
14 US8435732B2
Chimeric construct of mungbean yellow mosaic india virus (MYMIV) and its uses thereof
Publication/Patent Number: US8435732B2 Publication Date: 2013-05-07 Application Number: 12/746,429 Filing Date: 2008-12-08 Inventor: Chattopadhyay, Debasis   Yadav, Rajiv Kumar   Shukla, Rakesh Kumar   Assignee: National Institute for Plant Genome Research   IPC: C12Q1/70 Abstract: A recombinant DNA construct, recombinant vectors and host cells comprising the dimers of DNA A and DNA B of Mungbean Yellow Mosaic India Virus (MYMIV) in a single Ti plasmid are provided herein.
15 WO2012111021A8
SUBSTITUTED 1
Publication/Patent Number: WO2012111021A8 Publication Date: 2013-07-25 Application Number: 2012000053 Filing Date: 2012-01-24 Inventor: Saxena, Anil Kumar   Nath, Chandishwar   Roy, Kuldeep Kumar   Tota, Santoshkumar   Shukla, Rakesh   Assignee: Council of Scientific & Industrial Research   SAXENA, ANIL KUMAR   NATH, CHANDISHWAR   ROY, KULDEEP KUMAR   TOTA, SANTOSHKUMAR   SHUKLA, RAKESH   IPC: A61K31/47 Abstract: The present invention relates to novel substituted 1
16 US2013324573A1
SUBSTITUTED 1, 2, 3, 4-TETRAHYDROQUINOLIN-7-YL CARBAMATES AS ACETYLCHOLINESTERASE INHIBITORS FOR TREATMENT OF ALZHEIMER'S DISEASE
Publication/Patent Number: US2013324573A1 Publication Date: 2013-12-05 Application Number: 13/984,998 Filing Date: 2012-01-24 Inventor: Roy, Kuldeep Kumar   Tota, Santoshkumar   Nath, Chandishwar   Shukla, Rakesh   Saxena, Anil Kumar   Assignee: Council of Scientific & Industrial Research   IPC: C07D215/20 Abstract: The present invention relates to novel substituted 1,2,3,4-tetrahydroquinolin-7-yl carbamates, their preparation, and use as therapeutic agents, particularly in the prevention or treatment of neurodegenerative or Alzheimer's disease, or senile dementia, or memory disturbances, and more particularly to the prevention, treatment and amelioration of Alzheimer's disease with the novel substituted 1,2,3,4-tetrahydroquinolin-7-yl carbamates, which act as inhibitors of central cholinesterase enzymes, particularly acetylcholinesterase (AChE) following the indirect cholinomimetic pathway. The present invention particularly relates to compounds of formula A: Formula A wherein R1=alkyl, aryl, substituted aryl; R2═H, methyl; R3═H, alkyl, alkenyl, alkynyl, aralkyl, substituted aralkyl, aryl, heteroaryl. The present invention relates to novel substituted 1,2,3,4-tetrahydroquinolin-7-yl carbamates, their preparation, and use as therapeutic agents, particularly in the prevention or treatment of neurodegenerative or Alzheimer's disease, or senile dementia, or memory disturbances ...More ...Less
17 EP2675790A1
SUBSTITUTED 1, 2, 3, 4-TETRAHYDROQUINOLIN-7-YL CARBAMATES AS ACETYLCHOLINESTERASE INHIBITORS FOR TREATMENT OF ALZHEIMER'S DISEASE
Publication/Patent Number: EP2675790A1 Publication Date: 2013-12-25 Application Number: 12706943.3 Filing Date: 2012-01-24 Inventor: Roy, Kuldeep Kumar   Tota, Santoshkumar   Nath, Chandishwar   Shukla, Rakesh   Saxena, Anil Kumar   Assignee: Council of Scientific & Industrial Research   IPC: C07D215/20
18 WO2012111021A1
SUBSTITUTED 1
Publication/Patent Number: WO2012111021A1 Publication Date: 2012-08-23 Application Number: 2012000053 Filing Date: 2012-01-24 Inventor: Saxena, Anil Kumar   Nath, Chandishwar   Roy, Kuldeep Kumar   Tota, Santoshkumar   Shukla, Rakesh   Assignee: Council of Scientific & Industrial Research   SAXENA, ANIL KUMAR   NATH, CHANDISHWAR   ROY, KULDEEP KUMAR   TOTA, SANTOSHKUMAR   SHUKLA, RAKESH   IPC: A61K31/47 Abstract: The present invention relates to novel substituted 1
19 EP2227547A1
CHIMERIC CONSTRUCT OF MUNGBEAN YELLOW MOSAIC INDIA VIRUS (MYMIV) AND ITS USES THEREOF
Publication/Patent Number: EP2227547A1 Publication Date: 2010-09-15 Application Number: 08857252.4 Filing Date: 2008-12-08 Inventor: Chattopadhyay, Debasis   Yadav, Rajiv Kumar   Shukla, Rakesh Kumar   Assignee: National Institute For Plant Genome Research   IPC: C12N15/82
20 US2009150796A1
SYSTEM FOR AND METHOD OF PROVIDING A USER INTERFACE FOR A COMPUTER-BASED SOFTWARE APPLICATION
Publication/Patent Number: US2009150796A1 Publication Date: 2009-06-11 Application Number: 12/331,875 Filing Date: 2008-12-10 Inventor: Buttner, Karl   Orenchuk, Erich E.   Shukla, Rakesh   Assignee: 170 SYSTEMS, INC.   IPC: G06F3/048 Abstract: A system for providing a graphical interface to a user includes a server platform and an operating system and application software running thereon. The system includes a client device capable of running a standard web browser that accesses the software application on the server platform for displaying information to the user in a display area on the client device. The web browser displays the information without requiring additional software to be installed, downloaded or run on the client device, and without requiring a scripting language to be enabled in the web browser on the client. The application software facilitates user manipulation of unstructured data in the display area for detailed inspection, and facilitates the user selectively causing to display annotations within the display area. The application software facilitates the user inserting annotations within the display area, thereby causing an action to occur in this system or an external system. A system for providing a graphical interface to a user includes a server platform and an operating system and application software running thereon. The system includes a client device capable of running a standard web browser that accesses the software application on the server ...More ...Less