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1 US2010311879A1
REVERSE ADDITION PROCESS FOR PREPARATION OF REGIOREGULAR CONDUCTING POLYMERS
Publication/Patent Number: US2010311879A1 Publication Date: 2010-12-09 Application Number: 12/744,059 Filing Date: 2008-10-24 Inventor: Rieke, Reuben   Assignee: Reike Metals Inc.   IPC: C08L41/00 Abstract: The invention provides a method of preparing regioregular conducting polymers. The method includes adding a nickel (II) catalyst with the monomer-metal complex to provide the regioregular conducting polymer. Electronic devices can be made using the regioregular conducting polymers prepared as described herein. The invention provides a method of preparing regioregular conducting polymers. The method includes adding a nickel (II) catalyst with the monomer-metal complex to provide the regioregular conducting polymer. Electronic devices can be made using the regioregular conducting ...More Less
2 US2010311890A1
CURABLE COMPOSITIONS THAT FORM A LOW MODULUS POLYUREA
Publication/Patent Number: US2010311890A1 Publication Date: 2010-12-09 Application Number: 12/478,987 Filing Date: 2009-06-05 Inventor: Yakulis, Jr. George   Millero, Jr. Edward R.   Senkfor, Howard L.   Barancyk, Steven V.   Singer, Debra   Assignee: PPG INDUSTRIES OHIO, INC.   IPC: C08K3/36 Abstract: The present invention is directed to curable, two-package compositions comprising a first and second reactive package. The first reactive package comprises: a) a polyamine component comprising: i) an aspartic ester functional polyamine; and ii) an aromatic polyamine; and b) a rheology modifier. The second reactive package comprises a polyisocyanate, and the curable composition, upon mixing of the reactive packages, demonstrates a gel time of at least 10 minutes. The present invention is directed to curable, two-package compositions comprising a first and second reactive package. The first reactive package comprises: a) a polyamine component comprising: i) an aspartic ester functional ...More Less
3 US2010311895A1
LOW-K INTERLEVEL DIELECTRIC MATERIALS AND METHOD OF FORMING LOW-K INTERLEVEL DIELECTRIC LAYERS AND STRUCTURES
Publication/Patent Number: US2010311895A1 Publication Date: 2010-12-09 Application Number: 12/857,633 Filing Date: 2010-08-17 Inventor: Dubois, Geraud Jean-michel   Hedrick, James Lupton   Kim, Ho-cheol   Lee, Victor Yee-way   Magbitang, Teddie Peregrino   Miller, Robert Dennis   Sankarapandian, Muthumanickam   Sundberg, Linda Karin   Volksen, Willi   Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION   IPC: C08L83/06 Abstract: A composition of matter and a structure fabricated using the composition. The composition comprising: a resin; polymeric nano-particles dispersed in the resin, each of the polymeric nano-particle comprising a multi-arm core polymer and pendent polymers attached to the multi-arm core polymer, the multi-arm core polymer immiscible with the resin and the pendent polymers miscible with the resin; and a solvent, the solvent volatile at a first temperature, the resin cross-linkable at a second temperature, the polymeric nano-particle decomposable at a third temperature, the third temperature higher than the second temperature, the second temperature higher than the first temperature, wherein a thickness of a layer of the composition shrinks by less than about 3.5% between heating the layer from the second temperature to the third temperature. A composition of matter and a structure fabricated using the composition. The composition comprising: a resin; polymeric nano-particles dispersed in the resin, each of the polymeric nano-particle comprising a multi-arm core polymer and pendent polymers attached to the multi-arm ...More Less
4 US2010311901A1
ARAMID FILLED POLYIMIDES HAVING ADVANTAGEOUS THERMAL EXPANSION PROPERTIES, AND METHODS RELATING THERETO
Publication/Patent Number: US2010311901A1 Publication Date: 2010-12-09 Application Number: 12/848,408 Filing Date: 2010-08-02 Inventor: Kanakarajan, Kuppusamy   Frances, Arnold   Assignee: E. I. DU PONT DE NEMOURS AND COMPANY   IPC: C08L79/08 Abstract: The invention is directed to polyimide based adhesives having a coefficient of thermal expansion (“CTE”) equal to or below 50 ppm/° C. The adhesives of the present invention contain a polyimide base polymer present in the overall adhesive in an amount from 25 to 95 weight percent. The polyimide base polymer has a glass transition temperature (“Tg”) in a range of from about 150 to about 300° C. and typically has a coefficient of thermal expansion above 50 ppm/° C. The polyimide based adhesives of the invention also contain an aramid micro fiber filler in an amount from 5 to 75 weight percent, based upon the total weight of the polyimide based adhesive. The fiber filler can be used to lower CTE of the overall adhesive to match (or nearly match) the CTE of other materials like metal, silicon wafers, other polymers (including polyimide) and the like. The invention is directed to polyimide based adhesives having a coefficient of thermal expansion (“CTE”) equal to or below 50 ppm/° C. The adhesives of the present invention contain a polyimide base polymer present in the overall adhesive in an amount from 25 ...More Less
5 US2010311903A1
Photonic Shell-Core Cross Linked and Functionalized Nanostructures for Biological Applications
Publication/Patent Number: US2010311903A1 Publication Date: 2010-12-09 Application Number: 12/740,476 Filing Date: 2008-11-07 Inventor: Rajagopalan, Raghavan   Assignee: Rajagopalan, Raghavan   IPC: C08F287/00 Abstract: The present invention provides optical agents comprising optically functional cross linked supramolecular structures and assemblies useful for a range of imaging, diagnostic, and therapeutic applications. Supramolecular structures and assemblies of the present invention include optically functional shell-cross linked micelles wherein optical functionality is achieved via incorporation of one or more linking groups that include one or more photoactive moieties. The present invention further includes imaging, sensing and therapeutic methods using one or more optical agents of the present invention including optically functional shell cross-linked micelles. The present invention includes in situ monitoring methods, for example, wherein physical and/or structural changes in an optically functional shell-cross linked micelle generated in response to changes in chemical environment or physiological conditions causes a measurable change in the wavelengths or intensities of emission from the micelle. The present invention provides optical agents comprising optically functional cross linked supramolecular structures and assemblies useful for a range of imaging, diagnostic, and therapeutic applications. Supramolecular structures and assemblies of the present invention include ...More Less
6 US2010311963A1
CROSSLINKED-HYALURONIC ACID IN EMULSION
Publication/Patent Number: US2010311963A1 Publication Date: 2010-12-09 Application Number: 12/808,737 Filing Date: 2008-12-19 Inventor: Malle, Birgitte Moelholm   Assignee: Novozymes BioPharma DK A/S   IPC: C08B37/08 Abstract: The present invention relates to methods of producing crosslinked hyaluronic acid microbeads, as well as the produced microbeads, said method comprising the steps of: (a) mixing an aqueous alkaline solution comprising hyaluronic acid, or a salt thereof, with a solution comprising a crosslinking agent; (b) forming microdroplets having a desired size from the mixed solution of step (a) in an organic or oil phase to form a water in organic or water in oil (W/O) emulsion; (c) continuously stirring the W/O emulsion, whereby the reaction of hyaluronic acid with divinylsulfone takes place to provide crosslinked hyaluronic acid microbeads; and (d) purifying the crosslinked hyaluronic acid microbeads. The present invention relates to methods of producing crosslinked hyaluronic acid microbeads, as well as the produced microbeads, said method comprising the steps of: (a) mixing an aqueous alkaline solution comprising hyaluronic acid, or a salt thereof, with a solution ...More Less
7 US2010311972A1
METHOD FOR PRODUCING PHENOXYPYRIDINE DERIVATIVE
Publication/Patent Number: US2010311972A1 Publication Date: 2010-12-09 Application Number: 12/867,646 Filing Date: 2009-02-13 Inventor: Nagai, Mitsuo   Assignee: Nagai, Mitsuo   IPC: C07D401/14 Abstract: A method for producing a compound represented by the formula (I) the method comprising reacting in the presence of a condensation agent a compound represented by the formula (II) or a salt thereof with a compound represented by the formula (III) wherein R1 represents a 4-(4-methylpiperadin-1-yl) group or 3-hydroxyazetidin-1-yl group, R2, R3, R4 and R5 may be the same or different and each represents a hydrogen atom or a fluorine atom and R6 represents a hydrogen atom or a fluorine atom. A method for producing a compound represented by the formula (I) the method comprising reacting in the presence of a condensation agent a compound represented by the formula (II) or a salt thereof with a compound represented ...More Less
8 US2010312090A1
ATHEROSCLEROSIS RISK ASSESSMENT BY PROJECTED VOLUMES AND AREAS OF PLAQUE COMPONENTS
Publication/Patent Number: US2010312090A1 Publication Date: 2010-12-09 Application Number: 12/783,327 Filing Date: 2010-05-19 Inventor: Kerwin, William S.   Xu, Dongxiang   Yuan, Chun   Assignee: University of Washington Center for Commercialization   IPC: A61B5/055 Abstract: A novel technique directed toward risk assessment of a patient's plaque vulnerability, wherein clinical events may be caused by internal plaque components affecting a lumen within an artery. A surface area projection or shadow of one or more plaque components onto a lumen can be measured and assessed. Optionally, a total volume projection onto the lumen can also be measured and assessed to refine the determination of risk to a patient and to monitor the progression of atherosclerosis over time. A novel technique directed toward risk assessment of a patient's plaque vulnerability, wherein clinical events may be caused by internal plaque components affecting a lumen within an artery. A surface area projection or shadow of one or more plaque components onto a lumen can be ...More Less
9 US2010312105A1
METHODS FOR DIAGNOSING AND MONITORING TREATMENT OF LEWY BODY DEMENTIA BY ASSESSING DOPAMINE TRANSPORTER LEVEL
Publication/Patent Number: US2010312105A1 Publication Date: 2010-12-09 Application Number: 12/739,220 Filing Date: 2008-10-29 Inventor: Hurtt, Mark   Assignee: ALSERES PHARMACEUTICALS, INC.   IPC: A61B6/00 Abstract: A method of diagnosing Lewy Body Dementia in a human patient by assessing the level of dopamine transporter in at least one region of the patient's central nervous system, where a lowered level of dopamine transporter in the patient is indicative of Lewy Body Dementia. In embodiments of the invention, assessment of dopamine transporter levels includes assessing binding of a dopamine transporter ligand to the dopamine transporters using PET or SPECT. A method of diagnosing Lewy Body Dementia in a human patient by assessing the level of dopamine transporter in at least one region of the patient's central nervous system, where a lowered level of dopamine transporter in the patient is indicative of Lewy Body Dementia. In ...More Less
10 US2010312119A1
ULTRASONIC PROBE AND ULTRASONIC IMAGING APPARATUS
Publication/Patent Number: US2010312119A1 Publication Date: 2010-12-09 Application Number: 12/744,996 Filing Date: 2008-11-25 Inventor: Hashiba, Kunio   Izumi, Mikio   Asafusa, Katsunori   Assignee: Hashiba, Kunio   Izumi, Mikio   Asafusa, Katsunori   IPC: A61B8/14 Abstract: There is provided an ultrasound probe including a capacitive transducer for reducing multiple reflections while maintaining a pulse characteristic with which a high-quality image can be obtained, and is also provided an ultrasound imaging apparatus using the ultrasound probe. The ultrasound probe including the capacitive transducer is configured so as to satisfy the condition 6.5/fc<αd, where α [dB/mm/MHz] denotes the absorption coefficient of an acoustic lens, d [mm] denotes the maximum thickness of the acoustic lens, and fc [MHz] denotes the center frequency of the capacitive transducer, and satisfy the condition L<1/((3πfc)2×C), where L [H] denotes an inductance value per channel of the capacitive transducer, C [pF] denotes a capacitance per channel of the capacitive transducer, and fc [MHz] denotes the center frequency of the capacitive transducer. There is provided an ultrasound probe including a capacitive transducer for reducing multiple reflections while maintaining a pulse characteristic with which a high-quality image can be obtained, and is also provided an ultrasound imaging apparatus using the ultrasound probe ...More Less
11 US2010312125A1
System for Cardiac Pathology Detection and Characterization
Publication/Patent Number: US2010312125A1 Publication Date: 2010-12-09 Application Number: 12/754,644 Filing Date: 2010-04-06 Inventor: Zhang, Hongxuan   Assignee: SIEMENS MEDICAL SOLUTIONS USA, INC.   IPC: A61B5/021 Abstract: A system for heart performance characterization and abnormality detection includes an interface for receiving digitized electrical signals representing blood pressure waveforms over one or more heart beat cycles. The digitized electrical signals comprise, a first digital data sequence representing normal blood pressure of a patient, a second digital data sequence representing random blood pressure of a normal patient and a third digital data sequence representing a potentially abnormal blood pressure of a patient. A complexity processor calculates first, second and third complexity indices for the corresponding first, second and third digital data sequences respectively. A correlation processor uses the calculated first, second and third complexity indices to calculate one or more measures indicating deviation of the potentially abnormal blood pressure of the patient from a normal value. A system for heart performance characterization and abnormality detection includes an interface for receiving digitized electrical signals representing blood pressure waveforms over one or more heart beat cycles. The digitized electrical signals comprise, a first digital data ...More Less
12 US2010312128A1
SYSTEMS AND METHODS FOR MONITORING BLOOD PARTITIONING AND ORGAN FUNCTION
Publication/Patent Number: US2010312128A1 Publication Date: 2010-12-09 Application Number: 12/648,595 Filing Date: 2009-12-29 Inventor: Karst, Edward   Wenzel, Brian Jeffrey   Keel, Allen J.   Hou, Wenbo   Farazi, Taraneh Ghaffari   Assignee: Karst, Edward   Wenzel, Brian Jeffrey   Keel, Allen J.   Hou, Wenbo   Farazi, Taraneh Ghaffari   IPC: A61B5/0265 Abstract: Methods and systems for monitoring an organ of interest within a patient use one or more sensors to obtain one or more signals indicative of one or more of blood being provided to the organ of interest, blood being received from the organ of interest, and blood present in the organ of interest. Changes in an amount of blood being provided to the organ of interest, an amount of blood being received from the organ of interest, and/or an amount of blood present in the organ of interest are monitored based on changes in the obtained signal(s). Such methods and systems can be used to detect dysfunction of the organ of interest or tumor growth in the organ of interest, but are not limited thereto. Methods and systems for monitoring an organ of interest within a patient use one or more sensors to obtain one or more signals indicative of one or more of blood being provided to the organ of interest, blood being received from the organ of interest, and blood present in the ...More Less
13 US2010312137A1
Ovulation Cycle Monitoring and Management
Publication/Patent Number: US2010312137A1 Publication Date: 2010-12-09 Application Number: 12/084,166 Filing Date: 2006-10-24 Inventor: Gilmour, Robert   Blackwell, Leonard Francis   Assignee: Gilmour, Robert   Blackwell, Leonard Francis   IPC: A61B10/00 Abstract: Methods of monitoring the ovulation cycle of an animal by detecting specific analytes in body fluids, computer program products, devices, data processing systems, and kits for monitoring the ovulation cycle and determining the fertility of female mammals.
14 US2010312139A1
Method for Identifying Mammals at Risk for Elevated intracranial Pressure
Publication/Patent Number: US2010312139A1 Publication Date: 2010-12-09 Application Number: 12/793,820 Filing Date: 2010-06-04 Inventor: Dash, Pramod K.   Redell, John B.   Hergenroeder, Georgene   Moore, Anthony N.   Assignee: BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM   IPC: A61B5/00 Abstract: Disclosed are methods of diagnosing, screening and treating individuals at risk of elevated intracranial pressure based on detecting a transient decrease in serum ceruloplasmin and/or serum copper levels in the individual soon after occurrence of a head injury. This early drop in ceruloplasmin or copper level indicates an impending, potentially life threatening, elevation in the individual's intracranial pressure. Also disclosed are diagnostic applications and processes for identifying and producing diagnostic and prognostic assays useful for predicting elevated intracranial pressure, and test kits for performing such tests. Disclosed are methods of diagnosing, screening and treating individuals at risk of elevated intracranial pressure based on detecting a transient decrease in serum ceruloplasmin and/or serum copper levels in the individual soon after occurrence of a head injury. This early drop ...More Less
15 US2010312155A1
MASSAGE MACHINE AND CHAIR-TYPE MASSAGE APPARATUS
Publication/Patent Number: US2010312155A1 Publication Date: 2010-12-09 Application Number: 12/745,498 Filing Date: 2008-11-18 Inventor: Fukuyama, Yoshifumi   Shinomiya, Daisuke   Assignee: Family Co., Ltd.   IPC: A61H7/00 Abstract: A massage machine equipped with air cells (23a, 23b) disposed opposite to each other at a given distance therebetween in the up-down direction, a pair of support plates (22, 22) for supporting the air cells (23a, 23b) from the outside in the up-down direction, a pair of rotation portions (21) for applying a drive force to the pair of support plates (22, 22) in the front-rear direction and for supporting the support plates (22, 22) on both the left and right sides, guide portions (25) formed in the pair of rotation portions (21) to support the pair of support plates (22) so that the pair of support plates is movable in a direction in which the support plates (22) approach and separate from each other, biasing portions (26) for biasing the pair of support plates (22) in a direction in which the support plates approach each other, and a drive unit (28) for applying a rotation drive force to the rotation portions (21). A massage machine equipped with air cells (23a, 23b) disposed opposite to each other at a given distance therebetween in the up-down direction, a pair of support plates (22, 22) for supporting the air cells (23a, 23b) from the outside in the up-down direction, a pair of rotation ...More Less
16 US2010312169A1
Method of operating a vitrectomy probe
Publication/Patent Number: US2010312169A1 Publication Date: 2010-12-09 Application Number: 12/567,919 Filing Date: 2009-09-28 Inventor: Auld, Jack R.   Huculak, John C.   Assignee: Auld, Jack R.   Huculak, John C.   IPC: A61F9/007 Abstract: An improved method of operating a vitrectomy probe is disclosed in which the amount of time that the probe port is open during each cut cycle of the probe is fixed and minimized over all cut rates of the probe.
17 US2010312185A1
DEVICE SUITABLE FOR ADMINISTERING MUTUALLY INCOMPATIBLE LIQUID SUBSTANCES INTO THE HUMAN BODY
Publication/Patent Number: US2010312185A1 Publication Date: 2010-12-09 Application Number: 12/676,812 Filing Date: 2008-09-08 Inventor: Petrone, Dario   Cavicchioli, Mirco   Assignee: Petrone, Dario   Cavicchioli, Mirco   IPC: A61M39/10 Abstract: An object of the present invention is an apparatus for administering liquids into the human body characterized in that it has at least one main loading channel provided with at least one main administration point able to be connected to at least one container holding the liquid and at least one secondary loading channel, separated from the first by a membrane, provided with at least one container holding the liquid. Such apparatus allows the independent and simultaneous administration of liquids incompatible with each other, into the human body. An object of the present invention is an apparatus for administering liquids into the human body characterized in that it has at least one main loading channel provided with at least one main administration point able to be connected to at least one container holding the liquid ...More Less
18 US2010312186A1
SOFT TISSUE DISSECTOR
Publication/Patent Number: US2010312186A1 Publication Date: 2010-12-09 Application Number: 12/797,067 Filing Date: 2010-06-09 Inventor: Suchdev, Rachana S.   Regan, David L.   Martone, Stephen M.   Srivastava, Nilendu   Douglas, Gary   Assignee: Vascular Technology Inc.   IPC: A61M37/00 Abstract: A system for the dissection of soft tissue is provided, the system comprising: a dissection tip, the tip having a rigid, non-absorptive, end shell; the rigid end shell having a textured exterior surface configured to purchase soft tissue and having at least one porosity; and the dissection tip being configured to be coupled to a suction source. A system for the dissection of soft tissue is provided, the system comprising: a dissection tip, the tip having a rigid, non-absorptive, end shell; the rigid end shell having a textured exterior surface configured to purchase soft tissue and having at least one porosity; and the ...More Less
19 US2010312188A1
Body-Associated Receiver and Method
Publication/Patent Number: US2010312188A1 Publication Date: 2010-12-09 Application Number: 12/673,326 Filing Date: 2009-12-15 Inventor: Robertson, Timothy   Omidvar, Fataneh   Behzadi, Yashar   Arne, Lawrence   Rowberry, Kenneth   Hutchison, James   Leichner, Robert   Savage, George   Thompson, Andrew   Zdeblick, Mark   Kreidler, Marc   Hafezi, Hooman   Duck, Robert   Assignee: Robertson, Timothy   Omidvar, Fataneh   Behzadi, Yashar   Arne, Lawrence   Rowberry, Kenneth   Hutchison, James   Leichner, Robert   Savage, George   Thompson, Andrew   Zdeblick, Mark   Kreidler, Marc   Hafezi, Hooman   Duck, Robert   IPC: A61M5/20 Abstract: Receivers, which may be external or implantable, are provided. Aspects of receivers of the invention include the presence of one or more of: a high power-low power module; an intermediary module; a power supply module configured to activate and deactivate one or more power supplies to a high power processing block; a serial peripheral interface bus connecting master and slave blocks; and a multi-purpose connector. Receivers of the invention may be configured to receive a conductively transmitted signal. Also provided are systems that include the receivers, as well as methods of using the same. Additionally systems and methods are disclosed for using a receiver for coordinating with dosage delivery systems. Receivers, which may be external or implantable, are provided. Aspects of receivers of the invention include the presence of one or more of: a high power-low power module; an intermediary module; a power supply module configured to activate and deactivate one or more power ...More Less
20 US2010312194A1
SYRINGE WITH EXCHANGEABLE NEEDLE
Publication/Patent Number: US2010312194A1 Publication Date: 2010-12-09 Application Number: 12/679,056 Filing Date: 2008-09-19 Inventor: Leckebusch, Klaus   Assignee: HAMILTON BONADUZ AG   IPC: A61M5/00 Abstract: A syringe comprises a syringe body (12) having an axial inner recess (14) extending in the direction of a longitudinal axis of the syringe body (L), a piston (16) being guided in an axially moveable manner in said inner recess and contributing to the delimitation of a fluid-receiving volume together with a section of a wall (14a) radially delimiting the inner recess (14), and having a needle (24) that can be or is connected to a longitudinal end (12a) of the syringe body (12), wherein the needle (24) has a coupling geometry (28) at the longitudinal end (24a) thereof that is closer to the syringe body, wherein the needle (24) can be connected by said coupling geometry to a counter coupling geometry (30) of the syringe body (12), wherein the geometry composed of the coupling geometry (28) and counter coupling geometry (30) comprises an insertion section (32), which in the assembled state of the syringe (10) is received in a coupling recess (34) of the respectively other geometry, and wherein furthermore safety means (46) are provided, preventing a retraction movement of the insertion section (32) from the coupling recess (34) in the assembled state of the syringe (10). A syringe comprises a syringe body (12) having an axial inner recess (14) extending in the direction of a longitudinal axis of the syringe body (L), a piston (16) being guided in an axially moveable manner in said inner recess and contributing to the delimitation of a ...More Less