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1
US9527917B2
Publication/Patent Number: US9527917B2
Publication date: 2016-12-27
Application number: 14/854,908
Filing date: 2015-09-15
Abstract: Human antibodies, preferably recombinant human antibodies, both humanized and chimeric, which specifically bind to human OX40 are disclosed. Preferred antibodies have high affinity for OX40 receptor and activate the receptor in vitro and in vivo. The antibody can be a full-length antibody or an antigen-binding portion thereof. The antibodies, or antibody portions, are useful for modulating receptor activity, e.g., in a human subject suffering from a disorder in which OX40 activity is detrimental. Nucleic acids, vectors and host cells for expressing the recombinant human antibodies are provided, and methods of synthesizing the recombinant human antibodies, are also provided. Human antibodies, preferably recombinant human antibodies, both humanized and chimeric, which specifically bind to human OX40 are disclosed. Preferred antibodies have high affinity for OX40 receptor and activate the receptor in vitro and in vivo. The antibody can be a ...more ...less
2
US9527919B2
Publication/Patent Number: US9527919B2
Publication date: 2016-12-27
Application number: 14/562,269
Filing date: 2014-12-05
Abstract: The present invention provides novel high affinity antibodies and fragments thereof that bind to the cancer antigen PSCA. The antibodies of the present invention may be used for cancer diagnosis, prognosis, treatment, visualization, and the like. The Present invention also provides methods for the detection, visualization, and treatment of various cancers expressing PSCA. The present invention provides novel high affinity antibodies and fragments thereof that bind to the cancer antigen PSCA. The antibodies of the present invention may be used for cancer diagnosis, prognosis, treatment, visualization, and the like. The Present invention also ...more ...less
3
US9527927B2
Publication/Patent Number: US9527927B2
Publication date: 2016-12-27
Application number: 14/366,582
Filing date: 2012-12-18
Abstract: The technology relates in part to engineered antibodies. In particular, multispecific engineered antibodies. Such antibodies can be utilized for diagnostic and therapeutic applications in some aspects.
4
US9530263B1
Publication/Patent Number: US9530263B1
Publication date: 2016-12-27
Application number: 14/450,006
Filing date: 2014-08-01
Inventor: Daniel, Isaac S.  
Abstract: The present invention relates generally to a system and method of verification for access within site access areas using a wearable security device that includes one or more scannable frames displayed on the security device's exterior, wherein the wearer's identification information and assigned access for access to varied site access areas are electronically stored within the at least one scannable frame as embedded security clearance in multimedia format, which is verifiable when the at least one scannable frame is scanned by at least one image scanning device so that authorization to navigate within the premises is seamless within areas of authorized access while still allowing security to contain an individual in unauthorized locations. The present invention relates generally to a system and method of verification for access within site access areas using a wearable security device that includes one or more scannable frames displayed on the security device's exterior, wherein the wearer's identification ...more ...less
5
US9530267B1
Publication/Patent Number: US9530267B1
Publication date: 2016-12-27
Application number: 14/735,558
Filing date: 2015-06-10
Abstract: A coin hopper includes a hopper body including a housing having an accommodation chamber defined in a funnel-shaped coin box thereof and a coin outlet for guiding coins out of the accommodation chamber individually, a rotating wheel having multiple coin-pushing blades extended from a wheel base thereof and a coin-receiving space defined between each two adjacent coin-pushing blades, each coin-pushing blade having an abutment edge extending along one lateral side thereof for stopping one coin in one coin-receiving space and a pushing edge extending along an opposite lateral side thereof, a power drive adapted for rotating the rotating wheel to let coins be ruffled by coin-pushing blades and forced into coin-receiving spaces and then guided by arc-shaped abutment edges to move out of each coin-receiving space upwardly toward coin outlet one after another, and a coin-dispensing mechanism including a spring-loaded lever for pushing coins out of coin outlet individually. A coin hopper includes a hopper body including a housing having an accommodation chamber defined in a funnel-shaped coin box thereof and a coin outlet for guiding coins out of the accommodation chamber individually, a rotating wheel having multiple coin-pushing blades extended ...more ...less
6
US9530268B1
Publication/Patent Number: US9530268B1
Publication date: 2016-12-27
Application number: 14/753,230
Filing date: 2015-06-29
Abstract: The present invention relates generally to an ADA compliant coin recycler device that is capable of sorting a mixed denomination of coins, storing the coins and dispensing the desired amount of coins in the desired denomination. Additionally, the ADA compliant coin recycler device of the present invention also comprises a coin elevator assembly attached to the outside of the housing, which receives coins from the coin recycler and elevates the coins to an accessible height above the ADA's Standards for Accessible Design minimum reach requirement. The present invention relates generally to an ADA compliant coin recycler device that is capable of sorting a mixed denomination of coins, storing the coins and dispensing the desired amount of coins in the desired denomination. Additionally, the ADA compliant coin recycler ...more ...less
7
US9530273B2
Publication/Patent Number: US9530273B2
Publication date: 2016-12-27
Application number: 14/969,935
Filing date: 2015-12-15
Assignee: IGT
Abstract: Various embodiments of the present disclosure are directed to a gaming system and method providing a slot game employing a set of randomly selected reels. In one embodiment, the gaming system is configured to operate a slot game associated with a plurality of adjacently arranged reels including a plurality of symbols. Each of a plurality of the reels is associated with one of a plurality of different features and an indicator representing that feature. The gaming system begins sequentially displaying the reels and any corresponding indicators. The gaming system selects a set of two or more of the reels and stops sequentially displaying the reels such that the selected reels are displayed. The gaming system generates and displays a plurality of the symbols on the selected reels, determines whether any winning symbol combinations are displayed, determines any awards associated with any displayed winning symbol combinations, and displays any determined awards. Various embodiments of the present disclosure are directed to a gaming system and method providing a slot game employing a set of randomly selected reels. In one embodiment, the gaming system is configured to operate a slot game associated with a plurality of adjacently arranged ...more ...less
8
US9530276B2
Publication/Patent Number: US9530276B2
Publication date: 2016-12-27
Application number: 15/002,088
Filing date: 2016-01-20
Assignee: IGT
Abstract: When the player identifies herself to a gaming machine at a casino, for example by inserting a player tracking card into the card reader, she is, at generally the same time, logging onto a game provider's backend system (the game provider being different from the casino operator). This concurrent sign-on to the game provider's system is done in a non-intrusive, transparent, and passive manner. The player is not distracted from the normal steps leading to game play on the machine until she is ready to redeem points with the game provider or for some reason additional authentication is needed from the player. By virtue of this single sign-on to the game provider network, in addition to continuing game play across different casinos, the player can publish events to the Internet, such as on social networking sites, take advantage of offers targeted specifically for her, or facilitate responsible gaming programs. When the player identifies herself to a gaming machine at a casino, for example by inserting a player tracking card into the card reader, she is, at generally the same time, logging onto a game provider's backend system (the game provider being different from the casino ...more ...less
9
US9530279B2
Publication/Patent Number: US9530279B2
Publication date: 2016-12-27
Application number: 13/272,416
Filing date: 2011-10-13
Abstract: A wagering playing card game is played by: a dealer providing a set of playing cards; the dealer accepting at least one wager at a player position on an underlying playing card game; the dealer providing a first subset of exactly three random playing cards from the set of playing cards to a player position and dealer position; the dealer evaluates each player hand against the dealer hand as follows: a) a player position hand having all three cards with a rank below a predetermined rank automatically loses; b) a highest rank card from each player hand and the dealer hand play a game of war as a first sub-game, with the highest rank winning; c) a second highest rank card from each player hand and the dealer hand play a game of war as a second sub-game, with the highest rank winning; d) any ties void a sub-game. A wagering playing card game is played by: a dealer providing a set of playing cards; the dealer accepting at least one wager at a player position on an underlying playing card game; the dealer providing a first subset of exactly three ...more ...less